Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
A Simulation-Based Mechanical System-Identification Framework for Non-Invasive Lung Diagnostics and Personalized Pulmonary Rehabilitation. [PDF]
Postolache P +13 more
europepmc +1 more source
System Identification and Hybrid Model Predictive Control in Personalized mHealth Interventions for Physical Activity. [PDF]
El Mistiri M +3 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Retrieving interpretability to support vector machine regression models in dynamic system identification. [PDF]
Pena-Campos J +5 more
europepmc +1 more source
System Identification Methodology of a Gas Turbine Based on Artificial Recurrent Neural Networks. [PDF]
Aquize R +4 more
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
A Temperature Measurement and System Identification Method for Confined Cavity Explosions Based on an Improved Type C Thermocouple Sensor. [PDF]
Niu Z, Zhang J, Kong D, Jiang H, Kou M.
europepmc +1 more source
Quantum Linear System Algorithm for General Matrices in System Identification. [PDF]
Li K +6 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source

