Results 201 to 210 of about 2,196,650 (239)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

System Identification

open access: yes, 1970
Åström, Karl Johan, Eykhoff, Pieter
openaire   +1 more source
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QUANTUM SYSTEM IDENTIFICATION

International Journal of Quantum Information, 2005
The joint measurement approach has been shown to detect more information in quantum system. In this paper, we propose a quantum identification algorithm based on the joint quantum measurement. Through this, we can collectively compare an unknown quantum composite system with those in the database.
openaire   +1 more source

Bayesian System Identification

IFAC Proceedings Volumes, 1979
Abstract In Bayesian statistics the concept of probability is interpreted as a rational measure of belief which is used to descri be mathemat ically the uncertain re lation between the statistician and the external world. The statistical inference is understood as a correction of prior subject ive probability distribution by objective data. The paper
openaire   +2 more sources

Anaerobic Identification Systems

Clinics in Laboratory Medicine, 1985
Commercially produced prepackaged "kit" microsystems were evaluated for the identification of anaerobes. The API 20A and Minitek Anaerobe II systems by themselves were inadequate; even with the use of supplemental tests, agreement of identifications with a conventional method was only fair.
openaire   +2 more sources

System theory for system identification

Journal of Econometrics, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

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