Results 101 to 110 of about 18,821,561 (297)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Approach to Improving the 4DEnVar‐Initialized Deterministic Prediction Skill for Global Weather

open access: yesGeophysical Research Letters
Global deterministic numerical weather predictions (DNWPs) initialized from the ensemble mean analysis of four‐dimensional ensemble‐variational (4DEnVar) data assimilation are usually worse than those initialized by four‐dimensional variational (4DVar ...
Shujun Zhu   +14 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Business transformation architecture project : strategic plan

open access: yes, 2005
Title from p. [1] of PDF document (viewed Oct. 31, 2005).; "MAXIMUS, helping government serve the people"--P.
Ohio Administrative Knowledge System.
core  

Optimal state observation using quadratic boundedness: Application to UAV disturbance estimation

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2019
This paper presents the design of a state observer which guarantees quadratic boundedness of the estimation error. By using quadratic Lyapunov stability analysis, the convergence rate and the ultimate (steady-state) error bounding ellipsoid are ...
Cayero Julián   +3 more
doaj   +1 more source

Mini-review of sewage sludge parameters related to system modelling. [PDF]

open access: yesWaste Manag Res, 2023
Chang H   +4 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

PseudospectralNet: Toward Hybrid Atmospheric Models for Climate Simulations

open access: yesJournal of Advances in Modeling Earth Systems
Recent machine learning (ML) models have shown great success for weather prediction tasks, suggesting that atmospheric dynamics can in principle be learned from data.
Maximilian Gelbrecht   +2 more
doaj   +1 more source

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