Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
An Approach to Improving the 4DEnVar‐Initialized Deterministic Prediction Skill for Global Weather
Global deterministic numerical weather predictions (DNWPs) initialized from the ensemble mean analysis of four‐dimensional ensemble‐variational (4DEnVar) data assimilation are usually worse than those initialized by four‐dimensional variational (4DVar ...
Shujun Zhu +14 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Business transformation architecture project : strategic plan
Title from p. [1] of PDF document (viewed Oct. 31, 2005).; "MAXIMUS, helping government serve the people"--P.
Ohio Administrative Knowledge System.
core
Optimal state observation using quadratic boundedness: Application to UAV disturbance estimation
This paper presents the design of a state observer which guarantees quadratic boundedness of the estimation error. By using quadratic Lyapunov stability analysis, the convergence rate and the ultimate (steady-state) error bounding ellipsoid are ...
Cayero Julián +3 more
doaj +1 more source
Mini-review of sewage sludge parameters related to system modelling. [PDF]
Chang H +4 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Special Issue "Complex Dynamic System Modelling, Identification and Control". [PDF]
Zhu Q, Fusco G, Na J, Zhang W, Azar AT.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
PseudospectralNet: Toward Hybrid Atmospheric Models for Climate Simulations
Recent machine learning (ML) models have shown great success for weather prediction tasks, suggesting that atmospheric dynamics can in principle be learned from data.
Maximilian Gelbrecht +2 more
doaj +1 more source

