Results 121 to 130 of about 18,821,561 (297)

Noise-driven bifurcations in a neural field system modelling networks of grid cells. [PDF]

J Math Biol, 2022
Carrillo JA, Holden H, Solem S.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Modelling and simulation framework for reactive transport of organic contaminants in bed-sediments using a pure java object - oriented paradigm [PDF]

, 2006
Numerical modelling and simulation of organic contaminant reactive transport in the environment is being increasingly relied upon for a wide range of tasks associated with risk-based decision-making, such as prediction of contaminant profiles ...
Go, J., Roberts, G., Stegemann, J., Allan, I.   +3 more
core  

Applying systems approaches to stakeholder and community engagement and knowledge mobilisation in youth mental health system modelling. [PDF]

Int J Ment Health Syst, 2022
Freebairn L, Song YJC, Occhipinti JA, Huntley S, Dudgeon P, Robotham J, Lee GY, Hockey S, Gallop G, Hickie IB.   +9 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Diagnosing Pandemic Disaster Risk Management through Impact Chains and Forensic Analysis: An Intertwined DRM Model and Key Lessons from the Hospital Network in Bucharest, Romania

International Journal of Disaster Risk Science
The COVID-19 pandemic has tested the limits of healthcare facilities around the world, disrupting the provision of essential preventive and curative services.
Andra-Cosmina Albulescu, Iuliana Armaș, Funda Atun, Cristina Savu   +3 more
doaj   +1 more source

The essential system model [PDF]

, 1991
A particular way of modelling communication in an organization is presented as a new basis for systems analysis. Speech act theory provides the theoretical foundation of this approach. The so-called essential system model is identified as a missing kind of model in systems analysis, the usage of which however could mean a major improvement of current ...
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Selected 'Starter kit' energy system modelling data for selected countries in Africa, East Asia, and South America (#CCG, 2021). [PDF]

Data Brief, 2022
Allington L, Cannone C, Pappis I, Cervantes Barron K, Usher W, Pye S, Brown E, Howells M, Zachau Walker M, Ahsan A, Charbonnier F, Halloran C, Hirmer S, Cronin J, Taliotis C, Sundin C, Sridharan V, Ramos E, Brinkerink M, Deane P, Gritsevskyi A, Moura G, Rouget A, Wogan D, Barcelona E, Niet T, Rogner H, Bock F, Quirós-Tortós J, Angulo-Paniagua J, Krishnamurthy S, Harrison J, To LS.   +32 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source