Results 131 to 140 of about 2,267,017 (307)
Analysis of Sequence Diagram Layout in Advanced UML Modelling Tools
Applied Computer Systems, 2016 System modelling using Unified Modelling Language (UML) is the task that should be solved for software development. The more complex software becomes the higher requirements are stated to demonstrate the system to be developed, especially in its dynamic ...
Ņikiforova Oksana +2 more
doaj +1 more source
Applying systems approaches to stakeholder and community engagement and knowledge mobilisation in youth mental health system modelling. [PDF]
Int J Ment Health Syst, 2022 Freebairn L +9 more
europepmc +1 more source
, 2005 These notes derive a number of technical results on nonlinear contraction theory, a comparatively recent tool for system stability analysis. In particular, they provide new results on the preservation of contraction through system combinations, a ...
Slotine, Jean-Jacques, Tabareau, Nicolas
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Selected 'Starter kit' energy system modelling data for selected countries in Africa, East Asia, and South America (#CCG, 2021). [PDF]
Data Brief, 2022 Allington L +32 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Using the max-p regions problem algorithm to define regions for energy system modelling. [PDF]
MethodsX, 2021 Fleischer CE.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Through-life modelling of nano-satellite power system dynamics [PDF]
, 2013 This paper presents a multi-fidelity approach to finding optimal, mission-specific power system configurations for CubeSats. The methodology begins with propagation of the orbit elements over the mission lifetime, via a continuous-time model, accounting ...
Greenland, Stephen +2 more
core