Results 41 to 50 of about 168,546,907 (282)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The expressions and behavior of solutions for nonlinear systems of rational difference equations

Journal of Innovative Applied Mathematics and Computational Sciences, 2022
In this paper, we investigate the form of the solutions of the following systems of difference equations of second order xn+1xn+1==xnyn−1xn+yn,yn+1=xn−1ynxn+yn,xnyn−1xn−yn,yn+1=xn−1ynxn−yn,   n=0,1,...,xn+1=xnyn−1xn+yn,yn+1=xn−1ynxn+yn,xn+1=xnyn−1xn−yn,
Kholoud N. Alharbi, E. M. Elsayed
doaj  

Eigenvalue Characterization of a System of Difference Equations [PDF]

Nonlinear Oscillations, 2004
We consider the system of difference equations $$u_i (k) = \lambda \mathop \sum \limits_{\ell = 0}^N g_i (k,\ell )P_i (\ell ,u_1 (\ell ),u_2 (\ell ),...,u_n (\ell )), k \in \{ 0,1,...,T\} , 1 \leqslant i \leqslant n,$$ where λ > 0 and T ≥ N ≥ 0. Our aim is to determine the values of λ for which the above system has a constant-sign solution.
Agarwal, R.P., O'Regan, D., P. J. Y. Wong   +2 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Symmetric nonlinear solvable system of difference equations

Electronic Journal of Qualitative Theory of Differential Equations
We show the theoretical solvability of the system of difference equations $$x_{n+k}=\frac{y_{n+l}y_n-cd}{y_{n+l}+y_n-c-d},\quad y_{n+k}=\frac{x_{n+l}x_n-cd}{x_{n+l}+x_n-c-d},\quad n\in\mathbb{N}_0,$$ where $k\in\mathbb{N}$, $l\in\mathbb{N}_0 ...
Stevo Stevic, Bratislav Iricanin, Witold Kosmala   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

On a Competitive System of Rational Difference Equations

Universal Journal of Mathematics and Applications, 2019
This paper aims to investigate the global stability and the rate of convergence of positive solutions that converge to the equilibrium point of the system of difference equations in the modeling competitive populations in the form $$ x_{n+1}^{(1)}=\frac{
Mehmet Gümüş
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source