Results 61 to 70 of about 290,059 (256)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exact Solutions of System of Fourth-Order Difference Equations

open access: yesPan-American Journal of Mathematics
In this paper, we derive the solutions of system difference equations xn+1 = xn−1yn−3 / yn−1(a + bxn−1yn−3), yn+1 = yn−1xn−3 / xn−1(c + dyn−1xn−3), n∈N0, where the parameters a, b, c, d are real numbers and the initial conditions x−i and y−i for (i = 0,
Messaoud Berkal, Raafat Abo-Zeid
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Stability Analysis of a System of Exponential Difference Equations

open access: yesDiscrete Dynamics in Nature and Society, 2014
We study the boundedness character and persistence, existence and uniqueness of positive equilibrium, local and global behavior, and rate of convergence of positive solutions of the following system of exponential difference equations: xn+1=(α1+β1e-xn ...
Q. Din, K. A. Khan, A. Nosheen
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On the solutions of a three-dimensional system of difference equations

open access: yesKuwait Journal of Science, 2015
In this paper, we obtain the explicit solutions of the three-dimensional system of difference equations with multiplicative terms, which extended some results in literature.
Yasin Yazlık   +2 more
doaj  

CALCULATION OF THERMODYNAMIC CHARACTERISTICSOF THE ASCENDING SWIRLING FLOW WITH FIVE SOURCES OF HEATING

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2017
Calculations of the thermodynamic characteristics of air flows were carried out when several local sources were heated by the underlying surface. The basic mathematical model is the complete system of Navier-Stokes equations with constant coefficients of
D. D. Barannikova, A. G. Obukhov
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Product-type system of difference equations of second-order solvable in closed form

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
This paper presents solutions of the following second-order system of difference equations $$x_{n+1}=\frac{y_n^a}{z_{n-1}^b},\qquad y_{n+1}=\frac{z_n^c}{x_{n-1}^d},\qquad z_{n+1}=\frac{x_n^f}{y_{n-1}^g},\qquad n\in N_0,$$ where $a,b,c,d,f,g\in Z$, and ...
Stevo Stevic
doaj   +1 more source

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