Results 101 to 110 of about 4,922,959 (296)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Internal audit of costs on fixed assets repair

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2016
The article focuses on the approaches to the process and methods of expenditure audit on repair and modernization of fixed assets and the author considers that there is no single approach to understanding the issue.
M.Yu. Samchyk
doaj  

Similarities and Differences Between Internal Auditing, Internal Public Auditing and Other Services [PDF]

open access: yes
The internal auditing is an independent, objective assurance and consulting activity designed to add value and improve an organization's operations. It helps an organization accomplish its objectives by bringing a systematic, disciplined approach to ...
Gheorghe SUCIU
core  

ID slicing and the automated factory [PDF]

open access: yes, 1982
The automation of the slicing system utilizing internal-diameter saws for the production of the silicon wafers used in solar arrays is discussed.
Lewandowski, T.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Power plants automation and control using PLC tehnology [PDF]

open access: yes
This paper describes the Advanced System Simulator ASIMA that uses a microprocessor for its internal functions. In the existing configuration, a Siemens Simatic S7 300 is used to study different the control functions.
Arghira Nicoleta   +3 more
core  

Stabilization of mechanical systems using controlled Lagrangians [PDF]

open access: yes, 1997
We propose an algorithmic approach to stabilization of Lagrangian systems. The first step involves making admissible modifications to the Lagrangian for the uncontrolled system, thereby constructing what we call the controlled Lagrangian.
Bloch, Anthony M.   +2 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Pengaruh Faktor Internal Dan Eksternal Perusahaan Terhadapaudit Delay Pada Perusahaan Telekomunikasi Dan Transportasi Yang Terdaftar Di Bursa Efek Indonesia Pada Tahun 2010-2012 [PDF]

open access: yes, 2015
The objective of this research is to examine the influence of internal factors (firm size, profitability, solvability, internal control system) and external factor ( public accountant size) on the audit delay at a telecommunication and transportation ...
Anggraini, R. (Riska)   +2 more
core  

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