Results 101 to 110 of about 4,922,959 (296)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Internal audit of costs on fixed assets repair
The article focuses on the approaches to the process and methods of expenditure audit on repair and modernization of fixed assets and the author considers that there is no single approach to understanding the issue.
M.Yu. Samchyk
doaj
Similarities and Differences Between Internal Auditing, Internal Public Auditing and Other Services [PDF]
The internal auditing is an independent, objective assurance and consulting activity designed to add value and improve an organization's operations. It helps an organization accomplish its objectives by bringing a systematic, disciplined approach to ...
Gheorghe SUCIU
core
ID slicing and the automated factory [PDF]
The automation of the slicing system utilizing internal-diameter saws for the production of the silicon wafers used in solar arrays is discussed.
Lewandowski, T.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Power plants automation and control using PLC tehnology [PDF]
This paper describes the Advanced System Simulator ASIMA that uses a microprocessor for its internal functions. In the existing configuration, a Siemens Simatic S7 300 is used to study different the control functions.
Arghira Nicoleta +3 more
core
Stabilization of mechanical systems using controlled Lagrangians [PDF]
We propose an algorithmic approach to stabilization of Lagrangian systems. The first step involves making admissible modifications to the Lagrangian for the uncontrolled system, thereby constructing what we call the controlled Lagrangian.
Bloch, Anthony M. +2 more
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Pengaruh Faktor Internal Dan Eksternal Perusahaan Terhadapaudit Delay Pada Perusahaan Telekomunikasi Dan Transportasi Yang Terdaftar Di Bursa Efek Indonesia Pada Tahun 2010-2012 [PDF]
The objective of this research is to examine the influence of internal factors (firm size, profitability, solvability, internal control system) and external factor ( public accountant size) on the audit delay at a telecommunication and transportation ...
Anggraini, R. (Riska) +2 more
core

