Results 141 to 150 of about 170,074,763 (296)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hierarchical multi-label structuring of Japanese SOAP clinical notes with large language models. [PDF]

Sci Rep
Zhang Z, Tang M, Han F, Kitai H, Hirata K, Ogasawara K, Konno S, Kudo K.   +7 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

University of Texas System Reports

, 2012
Annual financial report by The University of Texas System Administration documenting income, expenditures, and other relevant financial information for fiscal year ...
University of Texas System
core  

Clinical AI and Precision Medicine: Philosophical Questions About Labels, Disease, and Evidence. [PDF]

J Med Syst
Armoundas AA.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

IDENTIFYING CONSUMER VALUATION PATTERNS OF ALTERNATIVE NUTRITION AND HEALTH LABELS COMBINATIONS: EVIDENCE FROM SPAIN [PDF]

The provision of nutrition and health information on food labels is increasing as an industry and regulation answer to the growing consumer concern with diet-health relationships.
de Magistris, Tiziana, Gracia, Azucena, Barreiro-Hurle, Jesus   +2 more
core  

AI powered patient records analysis for injury surveillance in children and adolescents - a feasibility study from Switzerland. [PDF]

Int J Public Health
Feer S, Saaro FM, Zysset A, Bächli M, Nieman S, Meier D, Seiler M, Bogojeska J, Dratva J.   +8 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Automated seismic fault mapping using convolutional neural networks for the Berenice Field, Western Desert, Egypt. [PDF]

Sci Rep
Amer M, Mabrouk WM, Eid AM, Metwally A.
europepmc   +1 more source