Results 101 to 110 of about 3,794,455 (268)

Architecting Systems of Systems with Different Levels of Centralized Decision-Making

Engineering Proceedings
Systems developed and operated by different stakeholders are increasingly interconnected. When multiple systems collaborate in a shared environment and together provide emerging functionalities, they are referred to as systems of systems.
Jasamin Akbari, Giuseppa Donelli, Luca Boggero, Björn Nagel   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Governing the Recovery of Stalled Systems-of-Systems: ADAPT, a Dependency-Anchored Methodology, with Multi-Case Feasibility Illustrations

Systems
Systems-of-systems (SoSs) integrate constituents that retain operational and managerial independence, and that independence leaves their engineering artifacts prone to drift: changes fail to propagate, misalignment surfaces late, and outputs accumulate ...
Elias Calboreanu
doaj   +1 more source

The Whole Body as the System in Systems Immunology. [PDF]

iScience, 2020
Poon MML, Farber DL.
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Aerial Firefighting Fleet for Wildfire Suppression: A System of Systems Approach

Engineering Proceedings
This study documents the design, development, and evaluation of a purpose-built aerial firefighting fleet optimized for diverse wildfire suppression environments as part of the COLOSSUS project’s X-Challenge.
Auraluck Pichitkul, Kaung Sett Toe, Kyaw Zaw Hlyan, Soe Yu Waddy, Aung Hein Kyaw, Nikolaos Kalliatakis, Nabih Naeem, Prajwal Shiva Prakasha   +7 more
doaj   +1 more source

A System of Systems of Mental Health in Cities, Digging Deep into the Origins of Complexity. [PDF]

Adm Policy Ment Health, 2020
Moustaid E, Kornevs M, Lindencrona F, Meijer S.   +3 more
europepmc   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source