Results 241 to 250 of about 417,746 (317)

AC frequency effects on high-throughput electrospinning for nanofibre production. [PDF]

Sci Rep
Batka O, Friedrich O, Skrivanek J, Valtera J, Zabka P, Bilek M, Mikule J, Beran J.   +7 more
europepmc   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Ambient Artificial Intelligence Use and Clinician Documentation Burden, Productivity, and Efficiency.

JAMA Netw Open
Husa RA, Haggerty J, Nute AW, Levine J, Love K, Martinez X, Parrish C.   +6 more
europepmc   +1 more source

Millets for food and nutritional security in semi-arid Bundelkhand, India: historical, scientific, and socio-economic perspectives. [PDF]

Front Nutr
Khan R, Sahoo S, Yadav S, Tiwari JK, Rout AK, Kumar N, Singh MK, Joshi DC, Reddy PS.   +8 more
europepmc   +1 more source

A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems

Advanced Science, EarlyView.
This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan, Zheng Li, Yunfei Chen, Mingting Du, Qianyi Wu, Congcong Miao, Tao Xu, Shan Wu, Xitao Chen, Xingwei Huang, Yuhui Cheng, Chengcheng Li, Yi Xin, Yandu Lu   +13 more
wiley   +1 more source

Economic Burden of COVID-19 Hospitalization in Almaty, Kazakhstan. [PDF]

Clinicoecon Outcomes Res
Akhmetzhan A, Abikulova A, Mamyrkul M, Medeulova A, Nassyrova NB, Faizullina K.   +5 more
europepmc   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Agronomic and Physiological Aspects of Programmed Cycle Pruning in <i>Coffea arabica</i>. [PDF]

Plants (Basel)
Baitelle DC, Freitas SJ, Vieira HD, Verdin Filho AC, Berilli SDS, Freitas ILJ, Rodrigues WP, Baroni DF, Freitas SP, Miranda GB, Arndt S, Tavares OCH, Dalvi LP, Santos PCD.   +13 more
europepmc   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Economic evaluations of preventive interventions for self-harm and suicide: a systematic review. [PDF]

Psychol Med
Le LK, Le DQ, Le PH, Tan EJ, Neil A, Andriessen K, Pirkis J, Mihalopoulos C, Reifels L.   +8 more
europepmc   +1 more source