Results 41 to 50 of about 417,746 (317)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Assessing cropping systems and mustard varieties for enhanced system yield and profitability: strategies for climate resilience in arid Western Rajasthan

open access: yesFrontiers in Sustainable Food Systems
ContextMustard (Brassica juncea L.) is a major oilseed crop in India, particularly suited to arid and semi-arid regions like Rajasthan, where low soil fertility, erratic rainfall, and limited irrigation resources constrain productivity.
Madan Lal Reager   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Superannuation: alternative default models [PDF]

open access: yes, 2016
This paper was released on 20 September 2016 to assist participants in preparing a submission to the public inquiry into Superannuation Alternative Default Models. It outlines a range of issues about which the Commission is seeking information.
Productivity Commission
core  

Soil Quality Index as a Predictor of Maize–Wheat System Productivity Under Long-Term Nutrient Management

open access: yesLand
The long-term effects of integrated nutrient management (INM) on crop performance and soil health—particularly within sub-humid environments—remain insufficiently explored.
Deepika Suri   +9 more
doaj   +1 more source

Soil carbon dynamics and productivity of rice–rice system under conservation tillage in submerged and unsubmerged ecologies of Eastern Indian Himalaya

open access: yesCarbon Management, 2019
Intensive tillage practices along with improper residue management in a rice (Oryza sativa)–rice system (RRS) contributed to soil fatigue and declining productivity in South Asia.
Gulab Singh Yadav   +5 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The items and rate of implementation the lean management tools and techniques in Iran’s healthcare system

open access: yesمدیریت اطلاعات سلامت, 2015
Introduction: The goal of lean thinking is value creation and the eradication of waste. The purpose of this paper was systematic study of items and rate of implementation the lean management tools and techniques in Iran’s healthcare system.
Abbas Jahangiri
doaj  

Improving soil health and system productivity through conservation agriculture and weed management strategies in rice-maize cropping system

open access: yesFrontiers in Sustainable Food Systems
Conservation agriculture (CA)-based rice-maize cropping system (RMCS) can be the possible option for higher productivity and maintain soil health in the Indo Gangetic Plains. However, weed infestation remains the major constraint in its adoption.
Subhra Sahoo   +9 more
doaj   +1 more source

Contemporary nitrogen management in maize (Zea mays)–Indian mustard (Brassica juncea) cropping system for maximizing yield, water productivity and profitability

open access: yesThe Indian Journal of Agricultural Sciences, 2022
A field experiment was conducted during 2018–19 and 2019–20 at the research farm of ICAR-Directorate of Rapeseed-Mustard Research, Bharatpur, Rajasthan to evaluate the effect of organic and inorganic nitrogen sources on yield, water productivity, system
HAR VIR SINGH   +5 more
doaj   +1 more source

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