Results 121 to 130 of about 1,057,095 (301)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Performance Evaluation of Overcurrent Protection Relay Based on Relay Operation Time (ROT)

International Journal of Electrical Engineering and Applied Sciences, 2018
Protection system plays an important role in detecting the presence of disorders and may prevent damage that can caused interference. Thus, the reliability of the system to maintain continuity of supply to the load will be improved.
Mohd Hendra Hairi, Mohd Shahrieel Mohd Aras, Farhan Hanaffi, Marizan Sulaiman   +3 more
doaj   +2 more sources

Developing Distance Protection Scheme for Double Circuit Transmission Lines Integrated Into Wind Energy System

NTU Journal of Engineering and Technology
Wind energy integration into the grid presents a major challenge to the conventional Permissive Underreach Transfer Trip (PUTT) distance protection scheme.
Mohamad Hamdallah Mohammed, Ahmed Ateya Allu   +1 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Hobby Farms and Protection of Farmland in British Columbia [PDF]

Agricultural land protection near the urban-rural fringe is a goal of many jurisdictions, and none more so than British Columbia, Canada, which uses a provincial-wide zoning scheme to prevent subdivisions and non-agricultural uses of the land.
G. Cornelis van Kooten, Geerte Cotteleer, Tracy Stobbe   +2 more
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Enhanced pilot protection scheme for half-wavelength transmission line based on the conservation of traveling wave energy

International Journal of Electrical Power & Energy Systems
The half-wavelength transmission system is a viable technology for long-distance and large-capacity power transmission. It can safely and efficiently transmit a large amount of clean energy to remote load centers.
Yutao Tang, Hongchun Shu, Yue Dai, Yiming Han   +3 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Improved differential protection for two-terminal weak feed AC system considering negative sequence control coordination strategy

International Journal of Electrical Power & Energy Systems
The flexible DC transmission project of renewable energy has become an inevitable development trend for large-scale renewable energy grid connection. Its two-terminal weak feed AC system is often composed of 100 % power electronic power equipment.
Junjie Hou, Qiangqiang Gao, Yanfang Fan, Guobing Song, Xiaofang Wu, Wentao Yang, Runbin Cao, Faxi Peng   +7 more
doaj   +1 more source