Results 131 to 140 of about 1,057,095 (301)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

A Comprehensive Directional Overcurrent Protection Scheme for LVDC Microgrids Using Harmonic Voltage Injection: Analysis and Case Studies

IEEE Access
Low voltage DC microgrids represent a highly adaptable approach to bringing renewable power generation closer to consumers, however their large, bidirectional fault currents and quick settling times complicate traditional protection methods.
Christopher James Nardone, Talal Elemamali Sati, Maher A. Azzouz   +2 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A digital resource copyright protection scheme based on blockchain cross-chain technology

Heliyon
With the expansion of the digital publishing industry, copyright infringement of digital resources has become increasingly rampant. Blockchain technology offers a promising solution for copyright protection of digital resources.
Renqiang Xie, Min Tang
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Optimization of longitudinal impedance protection for hybrid cascaded HVDC transmission under improved Bhattacharyya distance algorithm

Xi'an Gongcheng Daxue xuebao
To enhance the robustness of longitudinal protection in LCC-MMC hybrid cascaded HVDC transmission systems, a longitudinal protection scheme of HVDC transmission based on longitudinal impedance and improved Bhattacharyya distance algorithm was proposed ...
WANG Shuzheng, LI Peilin, YANG Junwei, ZHANG Jinhua, SHI Yuan, LIU Kangli   +5 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Intelligent agents for advanced power system protection schemes

MATEC Web of Conferences
This study explores the incorporation of intelligent agents to improve power system safety, using several computational models including machine learning, rule-based systems, neural networks, and fuzzy logic. The research assesses the effectiveness and efficiency of these agents in promptly identifying, categorizing, and responding to faults in the ...
Igorevich Rozhdestvenskiy Oleg, Deepthi P.   +1 more
openaire   +2 more sources

Development and Performance of spark-resistant Micromegas Detectors

, 2011
The Muon ATLAS MicroMegas Activity (MAMMA) focuses on the development and testing of large-area muon detectors based on the bulk-Micromegas technology.
Iakovidis, George, Karakostas, Kostantinos, Schott, Matthias   +2 more
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