Results 101 to 110 of about 3,189,856 (298)

Reliability of voting in fault-tolerant software systems for small output spaces [PDF]

open access: yes
Under a voting strategy in a fault-tolerant software system there is a difference between correctness and agreement. An independent N-version programming reliability model is proposed for treating small output spaces which distinguishes between ...
Mcallister, David F.   +2 more
core   +1 more source

Reliability and maintainability assessment factors for reliable fault-tolerant systems [PDF]

open access: yes, 1984
A long term goal of the NASA Langley Research Center is the development of a reliability assessment methodology of sufficient power to enable the credible comparison of the stochastic attributes of one ultrareliable system design against others.
Bavuso, S. J.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Aging Behavior of Silicone Rubber Seals During Long-term Storage

open access: yesCailiao gongcheng, 2018
The aging behavior of silicone rubber seals during long-term storage was studied by scanning electron microscope, attenuated total reflection-Fourier transform infrared spectroscopy, pyrolysis gas chromatography-mass spectrometry, thermogravimetric ...
ZHOU Kun, LIU Jie, ZHAO Yu
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Reliability of Mechanical System of Systems

open access: yesComputer Science & Information Technology, 2018
In this paper, we present a new methodology about reliability of systems of systems. We present also an example which combines the information transformation in complex systems and virtual design of this system based on finite element analysis. This example is help to balance the performances and the costs in complex system, or provide the optimal ...
El Hami, Abdelkhalak, Itmi, Mhamed
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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