Results 121 to 130 of about 314,793 (282)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Evaluasi Usability Aplikasi Tiket.com Menggunakan Metode System Usability Scale (SUS)

open access: yesCSRID (Computer Science Research and Its Development Journal)
Studi ini berfokus pada evaluasi kegunaan platform pemesanan tiket online, Tiket.com, yang meskipun populer, telah menerima banyak ulasan negatif dari pengguna. Tujuan utama dari penelitian ini adalah untuk menilai kegunaan platform tersebut guna mengidentifikasi area perbaikan yang dapat meningkatkan pengalaman pengguna.
Via Alfilaeni   +2 more
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Usability Evaluation of Wearable Smartwatches Using Customized Heuristics and System Usability Scale Score

open access: yesFuture Internet
The mobile and wearable nature of smartwatches poses challenges in evaluating their usability. This paper presents a study employing customized heuristic evaluation and use of the system usability scale (SUS) on four smartwatches, along with their mobile
Majed A. Alshamari, Maha M. Althobaiti
doaj   +1 more source

Evaluasi Usability Aplikasi Mangusada Mobile Menggunakan System Usability Scale (SUS)

open access: yesJurnal Nasional Komputasi dan Teknologi Informasi (JNKTI)
Abstrak - Aplikasi Mangusada Mobile merupakan sistem reservasi online yang digunakan oleh Rumah Sakit Mangusada, Kabupaten Badung, Bali, untuk mempermudah pasien dalam melakukan pendaftaran layanan kesehatan. Namun, dalam implementasinya, masih ditemukan kendala terkait usability yang dapat memengaruhi pengalaman pengguna.
Ayu Ngurah Catur Aprillia Dewi   +1 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A Revision Control System for Image Editing in Collaborative Multimedia Design

open access: yes, 2018
Revision control is a vital component in the collaborative development of artifacts such as software code and multimedia. While revision control has been widely deployed for text files, very few attempts to control the versioning of binary files can be ...
Calefato, Fabio   +2 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Usability in learning management systems: A mixed-method analysis

open access: yesInternational Journal of Pioneering Technology and Engineering
Usability analysis in software has a critical role in creating useful products for users and obtaining the necessary feedback. Learning Management Systems (LMSs) are among the most frequently used software in distance education.
Pembe Pelin Koca, Hakan Özcan
doaj   +1 more source

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