Results 121 to 130 of about 316,923 (300)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Evaluasi Usability Aplikasi Tiket.com Menggunakan Metode System Usability Scale (SUS)

CSRID (Computer Science Research and Its Development Journal)
Studi ini berfokus pada evaluasi kegunaan platform pemesanan tiket online, Tiket.com, yang meskipun populer, telah menerima banyak ulasan negatif dari pengguna. Tujuan utama dari penelitian ini adalah untuk menilai kegunaan platform tersebut guna mengidentifikasi area perbaikan yang dapat meningkatkan pengalaman pengguna.
Via Alfilaeni, Dwi Krisbiantoro, Gustin Setyaningsih   +2 more
openaire   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Usability Evaluation of Wearable Smartwatches Using Customized Heuristics and System Usability Scale Score

Future Internet
The mobile and wearable nature of smartwatches poses challenges in evaluating their usability. This paper presents a study employing customized heuristic evaluation and use of the system usability scale (SUS) on four smartwatches, along with their mobile
Majed A. Alshamari, Maha M. Althobaiti
doaj   +1 more source

Evaluasi Usability Aplikasi Mangusada Mobile Menggunakan System Usability Scale (SUS)

Jurnal Nasional Komputasi dan Teknologi Informasi (JNKTI)
Abstrak - Aplikasi Mangusada Mobile merupakan sistem reservasi online yang digunakan oleh Rumah Sakit Mangusada, Kabupaten Badung, Bali, untuk mempermudah pasien dalam melakukan pendaftaran layanan kesehatan. Namun, dalam implementasinya, masih ditemukan kendala terkait usability yang dapat memengaruhi pengalaman pengguna.
Ayu Ngurah Catur Aprillia Dewi, I Nyoman Tri Anindia Putra   +1 more
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Mobile Technology in Medicine: Development and Validation of an Adapted System Usability Scale (SUS) Questionnaire and Modified Technology Acceptance Model (TAM) to Evaluate User Experience and Acceptability of a Mobile Application in MRI Safety Screening. [PDF]

Indian J Radiol Imaging, 2023
Cheah WH, Mat Jusoh N, Aung MMT, Ab Ghani A, Mohd Amin Rebuan H.   +4 more
europepmc   +1 more source

A Controlled Natural Language Interface for Semantic Media Wiki

, 2009
Despite their potential value as collaborative knowledge editing systems, semantic wikis present a number of usability challenges for human end users.
Bao, Jie, Braines, Dave, Jones, Gareth, Shadbolt, Nigel, Smart, Paul R   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Effect of Web Usability on Users’ Web Experience [PDF]

, 2012
The ease with which a website visitor can find what they need is positively correlated with visitor satisfaction(Institute for Dynamic Educational Advancement, 2008).
Herring, Molly
core   +1 more source