Results 131 to 140 of about 21,648,517 (282)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Usability Analysis of the SIPBSI Website using the System Usability Scale as a Basis for Interface Improvement Priorities

Sistemasi: Jurnal Sistem Informasi
The Information System of the Indonesian Badminton Association (SIPBSI) is a web-based system designed to manage athlete, club, and ranking data in an integrated manner.
Kieky Adrian Sarwono, Charitas Fibriani (SCOPUS ID=57192643331)   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Re-Assessing the Usability Metric for User Experience (UMUX) Scale

, 2016
Usability Metric for User Experience (UMUX) and its shorter form variant UMUX-LITE are recent additions to standardized usability questionnaires. UMUX aims to measure perceived usability by employing fewer items that are in closer conformance with the ...
Berkman, Mehmet Ilker, Karahoca, Dilek
core  

Spanish Version of the System Usability Scale for the Assessment of Electronic Tools: Development and Validation. [PDF]

JMIR Hum Factors, 2020
Sevilla-Gonzalez MDR, Moreno Loaeza L, Lazaro-Carrera LS, Bourguet Ramirez B, Vázquez Rodríguez A, Peralta-Pedrero ML, Almeda-Valdes P.   +6 more
europepmc   +1 more source

Usability Evaluation of the Mendeley Website Using System Usability Scale (SUS)

JURNAL RISET DAN APLIKASI TEKNIK INDUSTRI
A scientific paper is a writing that follows scientific principles and research ethics, supported by reference citations. Mendeley facilitates reference management; however, many students are not yet accustomed to using it. This study aims to evaluate the use of Mendeley and identify areas for improvement. The research method employed usability testing
Ni Luh Putu Lilis Sinta Setiawati, I Kadek Agus Hendriawan Putra, I Gusti Ngurah Bagus Hermaya Krisna, I Kadek Dony Suryadana   +3 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

PAON usability testing using system usability scale

Journal of Physics: Conference Series, 2019
K Setemen, L J Erawati Dewi, I K Purnamawan   +2 more
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source