Results 101 to 110 of about 24,523,468 (288)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

EVALUASI USABILITY SISTEM INFORMASI MANAJEMEN APOTEK BERBASIS PROGRESSIVE WEB APPLICATION MENGGUNAKAN METODE SYSTEM USABILITY SCALE

Jurnal Inovasi Pendidikan dan Teknologi Informasi
This study aims to evaluate the usability level of a Progressive Web App (PWA)-based pharmacy management information system called Siapotek, implemented at Apotek Madani.
Ichsandi, Ade Agung Kurniawan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Evaluasi Usability Aplikasi MyTelkomsel Menggunakan Metode System Usability Scale (SUS)

CESS (Journal of Computer Engineering, System and Science)
Aplikasi mobile yang user-friendly menjadi elemen kunci dalam menjaga kepuasan pengguna di era digital. MyTelkomsel, salah satu aplikasi seluler terkemuka di Indonesia, menghadapi tantangan dalam memastikan kegunaannya seiring dengan pengembangan fitur yang kompleks.
I Putu Prima Ananda, Ni Putu Ria Anggreni, I Made Agus Oka Gunawan, Gede Indrawan   +3 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Usability Assessment of Salud Electronic Dental Record System

Clinical, Cosmetic and Investigational Dentistry
Abdulwahhab Alshammari,1– 3 Mohammed Awawdeh,2– 4 Nawaf Hamoud Alsalwah,5 Sana Alnafrani,2,6,7 Suliman Alsaeed2– 4 1College of Public Health and Health Informatics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 2King ...
Alshammari A, Awawdeh M, Alsalwah NH, Alnafrani S, Alsaeed S   +4 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

SYSTEM USABILITY SCALE VS HEURISTIC EVALUATION

, 2022
Usability merupakan salah satu bidang ilmu untuk menganalisa atau menguji tingkat kemudahan penggunaan perangkat lunak. Usability atau yang sering dikenal dengan kebergunaan adalah teknik pengujian atau pengukuran aplikasi perangkat lunak yang ...
UNIVERSITAS BINA DARMA, UNIVERSITAS BINA DARMA
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source