Results 81 to 90 of about 42,961 (301)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

User Satisfaction Analysis of PDAM’s CATER System using Heuristic-SUS Evaluation

Sistemasi: Jurnal Sistem Informasi
The Regional Drinking Water Company (PDAM) of Salatiga City, as a provider of clean water services, has implemented a web-based Meter Recording System (CATER) to enhance operational efficiency.
Stefanus Adin Seno Purdayanto, Penidas Fiodinggo Tanaem   +1 more
doaj   +1 more source

The mHealth App Usability Questionnaire (MAUQ): Development and Validation Study

JMIR mHealth and uHealth, 2019
BackgroundAfter a mobile health (mHealth) app is created, an important step is to evaluate the usability of the app before it is released to the public.
Zhou, Leming, Bao, Jie, Setiawan, I Made Agus, Saptono, Andi, Parmanto, Bambang   +4 more
doaj   +1 more source

Psychometric Properties of the Persian Language Version of the System Usability Scale [PDF]

, 2014
Background: The System Usability Scale (SUS) is a widely used self–administered instrument for evaluating the usability of a wide range of products and services.
Iman Dianat, Mohammad AsghariJafarabadi, Zahra Ghanbari   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Evaluasi Usability pada Aplikasi Mobile ACC.ONE menggunakan System Usability Scale (SUS) dan Usability Testing

Jurnal Sains dan Informatika, 2021
Perusahaan pembiayaan kendaraan mobil saat ini semakin banyak dan berkembang begitu pesat. Setiap perusahaan berusaha untuk menarik perhatian pelanggan dengan berbagai cara, terutama peningkatan teknologi untuk mendukung dan memudahkan proses kegiatan pembiayaan mobil.
null Veni Manik, Clara Hetty Primasari, null Yohanes Priadi Wibisono, null Aloysius Bagas Pradipta Irianto   +3 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Statistical Analysis of System Usability Scale (SUS) Evaluations in Online Learning Platform

Journal of Information Systems and Informatics
This study evaluates the usability of a Moodle-based online learning system at a university using the System Usability Scale (SUS). Introduced in 2019, the platform has been instrumental in facilitating access to educational resources, enhancing the ...
Ozzi Suria
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source