Results 111 to 120 of about 3,721,345 (286)

A review of studies mapping (or cross walking) from non-preference based measures of health to generic preference-based measures [PDF]

open access: yes
This paper presents a systematic review of current practice in mapping between nonpreference based measures and generic preference-based measures.
Brazier, JE, Tsuchiya, A, Yang, Y
core   +1 more source

Water, Sanitation, Hygiene, and Nutrition in Bangladesh: Can Building Toilets Affect Children's Growth? [PDF]

open access: yes, 2016
This report provides a systematic review of the evidence to date, both published and grey literature, on the relationship between water and sanitation and nutrition.
Iffat Mahmud, Nkosinathi Mbuya
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Understanding schistosomiasis transmission: A systematic review of mathematical models

open access: yesScientific African
We employ PRISMA guidelines to carry out a systematic review of mathematical models of schistosomiasis organizing them into focus and approach based categories. Our analysis reveals a range of substantive challenges inherent in modelling disease dynamics,
Agatha Abokwara   +2 more
doaj   +1 more source

Outcome of secondary root canal treatment: a systematic review of the literature.

open access: yes, 2008
UNLABELLED: AIMS (I): To investigate the effects of study characteristics on the reported success rates of secondary root canal treatment (2 degrees RCT or root canal retreatment); and (ii) to investigate the effects of clinical factors on the success of
Gulabivala, K, Mann, V, Ng, Y-L
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A review of the effectiveness of lower limb orthoses used in cerebral palsy [PDF]

open access: yes, 2009
To produce this review, a systematic literature search was conducted for relevant articles published in the period between the date of the previous ISPO consensus conference report on cerebral palsy (1994) and April 2008.
Bowers, Roy, ISPO (Funder), Ross, Karyn
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Systematic literature review: teaching novices programming using robots

open access: yes15th Annual Conference on Evaluation & Assessment in Software Engineering (EASE 2011), 2011
Background: Teaching programming to novices is a difficult task due to the complex nature of the subject, as negative stereotypes are associated with programming and because introductory programming courses often fail to encourage student understanding.
Major, Louis   +2 more
openaire   +5 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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