Results 131 to 140 of about 1,048,730 (293)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Preoperative Hair Removal—a Systematic Literature Review [PDF]

open access: bronze, 2002
Inge Kjønniksen   +3 more
openalex   +1 more source

The Trend of Multimodal Use in School Learning from The Past to The Future : A Systematic Literature Review

open access: yesJurnal Kependidikan
This study aims to investigate the trends of multimodal use in school learning from the past to the future as an important reflection for education practitioners.
Dyah Worowirastri Ekowati   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

INTEGRASI CERITA RAKYAT DALAM PEMBELAJARAN BAHASA DAN SASTRA: TINJAUAN SISTEMATIS LITERATUR TERHADAP PENINGKATAN NILAI BUDAYA DAN IDENTITAS LOKAL

open access: yesSeBaSa
This study examines the integration of folklore into Indonesian language and literature learning to enhance students' understanding of cultural values and local identity.
Kaleb E. Simanungkalit   +3 more
doaj   +1 more source

Large language models streamline automated systematic review: A preliminary study [PDF]

open access: yesarXiv
Large Language Models (LLMs) have shown promise in natural language processing tasks, with the potential to automate systematic reviews. This study evaluates the performance of three state-of-the-art LLMs in conducting systematic review tasks. We assessed GPT-4, Claude-3, and Mistral 8x7B across four systematic review tasks: study design formulation ...
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Systematic Literature Review Terhadap Evaluasi Perangkat Lunak Tentang Serious Game

open access: yesJurnal Informatika, 2017
Abstrak Saat ini game merupakan perangkat lunak yang popular dikalangan anak-anak, remaja, dan dewasa. Selain itu, terdapat game yang memiliki tujuan tertentu selain sebagai media hiburan yang disebut dengan serious game.
Andhik Ampuh Yunanto, Siti Rochimah
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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