Results 111 to 120 of about 1,888,501 (343)

A model-driven method for the systematic literature review of qualitative empirical research [PDF]

open access: yes, 2012
This paper explores a model-driven method for systematic literature reviews (SLRs), for use where the empirical studies found in the literature search are based on qualitative research. SLRs are an important component of the evidence-based practice (EBP)
Edwards, Helen   +2 more
core   +1 more source

Optimal search strategies for identifying sound clinical prediction studies in EMBASE [PDF]

open access: yes, 2005
BACKGROUND: Clinical prediction guides assist clinicians by pointing to specific elements of the patient's clinical presentation that should be considered when forming a diagnosis, prognosis or judgment regarding treatment outcome.
A Laupacis   +25 more
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Impact of Baseline Magnetic Resonance Imaging on Neurologic, Functional, and Safety Outcomes in Patients With Acute Traumatic Spinal Cord Injury [PDF]

open access: yes, 2017
Study Design: Systematic review. Objective: To perform a systematic review to evaluate the utility of magnetic resonance imaging (MRI) in patients with acute spinal cord injury (SCI).
Aarabi, Bizhan   +10 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Risk of postoperative pulmonary complications in adult surgical patients with metabolic syndrome: a systematic review and meta-analysis protocol [PDF]

open access: yes, 2019
Background: Metabolic syndrome (MetS) is defined as an accumulation of risk factors that include chronic hypertension, dyslipidaemia, insulin resistance and obesity and leads to an increased risk for diabetes, cardiovascular disease and stroke.
Gow, Jeffrey   +4 more
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Governance of carbon dioxide removal: an AI-enhanced systematic map of the scientific literature

open access: yesFrontiers in Climate
IntroductionFor limiting global warming to well below 2°C rapid and stringent GHG emissions reductions are required. In addition, we also need to actively remove CO2 from the atmosphere via carbon dioxide removal (CDR).
Sarah Lück   +3 more
doaj   +1 more source

PRM32 Consistency In Search Strategies For Systematic Literature Reviews In Nice Submissions [PDF]

open access: yes, 2003
L'edifici fou construït l'any 1880, aproximadament.Primer pla d'edifici plurifamiliar entre mitgeres i formant cantonada. Consta de planta baixa, entresòl, quatre plantes pis, planta terrat i unes remuntes, algunes d¿elles probablement posteriors ...
Murphy, D, Guy, H, Hirst, A
core   +1 more source

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