Results 51 to 60 of about 82,566 (244)
A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück +13 morewiley +1 more sourceEvidence for an Excess of Soft Photons in Hadronic Decays of Z^0
, 2006 Soft photons inside hadronic jets converted in front of the DELPHI main
tracker (TPC) in events of qqbar disintegrations of the Z^0 were studied in the
kinematic range 0.2 < E_gamma < 1 GeV and transverse momentum with respect to
the closest jet ...141, 305, 408, 41, 43, 49, 51, 54, 548, 59, 67, A. Andreazza, A. Augustinus, A. Ballestrero, A. Baroncelli, A. Behrmann, A. Benvenuti, A. De Angelis, A. De Min, A. Di Simone, A. Ferrer, A. Hallgren, A. Lipniacka, A. Malek, A. Markou, A. Oblakowska-Mucha, A. Olshevski, A. Onofre, A. Ouraou, A. Oyanguren, A. Passeri, A. Perrotta, A. Petrolini, A. Pullia, A. Read, A. Romero, A. Sadovsky, A. Savoy-Navarro, A. Segar, A. Sisakian, A. Sokolov, A. Sopczak, A. Stocchi, A. Tonazzo, A. Zalewska, A. Zintchenko, A.C. Taffard, A.J. Washbrook, B. Asman, B. Bouquet, B. Buschbeck, B. De Lotto, B. Golob, B. Marechal, B. Muryn, B. Stugu, B. Tome, B.P. Kersevan, B.T. King, Balek, Balek, Barshay, Barshay, Barshay, Barshay, Botz, Burnett, C. Berat, C. De Clercq, C. Garcia, C. Haag, C. Joram, C. Kourkoumelis, C. Mariotti, C. Martinez-Rivero, C. Matteuzzi, C. Meroni, C. Parkes, C. Sander, C. Troncon, C. Weiser, Campagne, Catani, Chliapnikov, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Collaboration, Czyż, D. Bardin, D. Bertrand, D. Bloch, D. Crennell, D. Fassouliotis, D. Jeans, D. Liko, D. Loukas, D. Moraes, D. Reid, D. Rodriguez, D. Ryabtchikov, D. Treille, D. Vilanova, D. Wicke, D. Zavrtanik, Darbinian, Dosch, E. Anashkin, E. Ben-Haim, E. Brodet, E. Fokitis, E. Gazis, E. Graziani, E. Katsoufis, E. Migliore, E. Piotto, E.K. Johansson, F. Carena, F. Cavallo, F. Cossutti, F. Ferro, F. Fulda-Quenzer, F. Hauler, F. Kapusta, F. Ledroit, F. Mandl, F. Matorras, F. Mazzucato, F. Navarria, F. Parodi, F. Pierre, F. Richard, F. Tegenfeldt, F. Veloso, G. Borisov, G. Cosme, G. Della Ricca, G. Eigen, G. Fanourakis, G. Gomez-Ceballos, G. Grosdidier, G. Jarlskog, G. Kernel, G. Leder, G. Myatt, G. Polok, G. Smadja, G. Tristram, G. Valenti, G. Vegni, G. Wilkinson, G.J. Barker, Gribov, Gustavson, H. Foeth, H. Herr, H. Palka, H. Wahlen, Hove, Huang, I. Boyko, I. Van Vulpen, I.A. Tyapkin, J-C. Marin, J. Abdallah, J. Chudoba, J. Cuevas, J. Dalmau, J. Drees, J. D’Hondt, J. Fernandez, J. Fuster, J. Guy, J. Hoffman, J. Lamsa, J. Lemonne, J. MacNaughton, J. Marco, J. Masik, J. Montenegro, J. Piedra, J. Rames, J. Rehn, J. Ridky, J. Salt, J. Strauss, J. Timmermans, J. Van Eldik, J. Wickens, J.E. Augustin, J.H. Lopes, J.M. Brunet, J.M. Lopez, J.N. Jackson, J.P. Palacios, K-H. Becks, K. Cieslik, K. Doroba, K. Grzelak, K. Hamacher, K. Hamilton, K. Hultqvist, K. Moenig, K. Muenich, K. Nawrocki, K. Osterberg, L. Berntzon, L. de Paula, L. Di Ciaccio, L. Jungermann, L. Leinonen, L. Lyons, L. Mundim, L. Pape, L. Peralta, L. Pieri, L. Salmi, L. Tkatchev, L. Vitale, Landau, Lichard, Lichard, Lichard, Low, Lönnblad, M-L. Turluer, M. Battaglia, M. Baubillier, M. Begalli, M. Berggren, M. Besancon, M. Blom, M. Bluj, M. Bonesini, M. Boonekamp, M. Bracko, M. Calvi, M. Chapkin, M. Ellert, M. Elsing, M. Feindt, M. Gandelman, M. Hennecke, M. Kucharczyk, M. Margoni, M. Mazzucato, M. Moch, M. Mulders, M. Nassiakou, M. Nikolenko, M. Paganoni, M. Pimenta, M. Rivero, M. Siebel, M. Stanitzki, M. Szczekowski, M. Szeptycka, M. Tobin, M. Trochimczuk, M. Winter, M. Witek, M. Zupan, M.A. Houlden, M.C. Espirito Santo, M.E. Pol, M.J. Costa, N. Amapane, N. Anjos, N. Benekos, N. Besson, N. Castro, N. De Maria, N. Mastroyiannopoulos, N. Pukhaeva, N. van Remortel, N.I. Zimin, N.J. Kjaer, O. Botner, O. Kouznetsov, O. Passon, O. Smirnova, O. Yushchenko, P. Abreu, P. Adzic, P. Antilogus, P. Baillon, P. Bambade, P. Bruckman, P. Buschmann, P. Charpentier, P. Checchia, P. Chliapnikov, P. Collins, P. Gavillet, P. Goncalves, P. Jarry, P. Jonsson, P. Kluit, P. Kokkinias, P. Lutz, P. Morettini, P. Rebecchi, P. Renton, P. Ronchese, P. Roudeau, P. Tortosa, P. Travnicek, P. Tyapkin, P. Van Dam, P. Verdier, P. Zalewski, P.D. Johansson, P.J. Holt, P.P. Allport, P.S.L. Booth, Physics, Pisút, Quack, R. Alemany-Fernandez, R. Barbier, R. Brenner, R. Chierici, R. Contri, R. Gokieli, R. Leitner, R. Marco, R. Mc Nulty, R. Monge, R. Nicolaidou, R. Orava, R. Reinhardt, R. Sekulin, R. Sosnowski, S-O. Holmgren, S. Amato, S. Andringa, S. Ask, S. Haug, S. Katsanevas, S. Maltezos, S. Moreno, S. Paiano, S. Todorovova, S. Tzamarias, S.U. Chung, Shuryak, Sjöstrand, Sjöstrand, T. Albrecht, T. Alderweireld, T. Allmendinger, T. Camporesi, T. da Silva, T. Ekelof, T. Lesiak, T. Moa, T. Myklebust, T. Podobnik, T. Rovelli, T. Spassov, T. Szumlak, T. Tabarelli, T.J.V. Bowcock, Th.D. Papadopoulou, U. Amaldi, U. Flagmeyer, U. Kerzel, U. Mjoernmark, U. Mueller, U. Parzefall, U. Schwickerath, V. Canale, V. Hedberg, V. Lepeltier, V. Obraztsov, V. Perepelitsa, V. Poireau, V. Pozdniakov, V. Ruhlmann-Kleider, V. Uvarov, V. Verzi, V. Vrba, V. Zhuravlov, W-D. Apel, W. Adam, W. Da Silva, W. De Boer, W. Liebig, W. Mitaroff, W. Murray, W. Venus, Y. Arnoud, Z. Krumstein +408 morecore +4 more sourcesOn the Error Performance of Systematic Polar Codes
, 2015 Systematic polar codes are shown to outperform non-systematic polar codes in terms of the bit-error-rate (BER) performance. However theoretically the mechanism behind the better performance of systematic polar codes is not yet clear. In this paper, we set the theoretical framework to analyze the performance of systematic polar codes.Li, Liping, Zhang, Wenyi, Hu, Yanjunopenaire +2 more sourcesCytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock +10 morewiley +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourcePlecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor +10 morewiley +1 more source