Results 141 to 150 of about 5,876,056 (368)
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Corticosteroids and the Pharmacological Management of Autism—An Integrative Review
Scientia PharmaceuticaAutism spectrum disorder (ASD), or autism, is a lifelong neurodevelopmental condition typically detected during early childhood, for which no specific and efficient pharmacological management is currently available.
Lillian Amanda Gabarrão de Jesus +3 more
doaj +1 more source
Position: The AI Conference Peer Review Crisis Demands Author Feedback and Reviewer Rewards [PDF]
arXivThe peer review process in major artificial intelligence (AI) conferences faces unprecedented challenges with the surge of paper submissions (exceeding 10,000 submissions per venue), accompanied by growing concerns over review quality and reviewer responsibility. This position paper argues for the need to transform the traditional one-way review system
arxiv
Book Review: III. Systematic and Apologetic Theology: Jesus als Charakter [PDF]
, 1907 E. Y. Mullins
openalex +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Pharmacological Research, 2023 The burden of metabolic disorders is alarmingly increasing globally. On the other hand, sustainability is the key project of the 21st century. Natural products offer a coherent option for the complementary management of both these challenges.
Amene Saghazadeh
doaj
Crowdsourcing Information Extraction for Biomedical Systematic Reviews [PDF]
arXiv, 2016 Information extraction is a critical step in the practice of conducting biomedical systematic literature reviews. Extracted structured data can be aggregated via methods such as statistical meta-analysis. Typically highly trained domain experts extract data for systematic reviews.
arxiv
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Frontiers in Clinical Diabetes and HealthcareBackgroundType 2 diabetes mellitus (T2DM) is a significant global health challenge whose prevalence is projected to increase alarmingly. Recently, due to better safety and fewer adverse effects, herbal medicines have been used to manage T2DM.
Mehdi Karimi +7 more
doaj +1 more source
Enhancing Systematic Reviews with Large Language Models: Using GPT-4 and Kimi [PDF]
arXivThis research delved into GPT-4 and Kimi, two Large Language Models (LLMs), for systematic reviews. We evaluated their performance by comparing LLM-generated codes with human-generated codes from a peer-reviewed systematic review on assessment. Our findings suggested that the performance of LLMs fluctuates by data volume and question complexity for ...
arxiv