Results 181 to 190 of about 6,467,255 (355)

Standard cardiopulmonary resuscitation versus chest compressions only after out-of-hospital cardiac arrest: a protocol for systematic review and meta-analysis [PDF]

, 2021
Qin Qin
openalex   +1 more source

Literature reviews vs systematic reviews [PDF]

Australian and New Zealand Journal of Public Health, 2015
Priscilla Robinson, John Lowe
openaire   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

POS0145 PREDICTORS OF PSORIATIC ARTHRITIS DEVELOPMENT IN PSORIASIS PATIENTS: A SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS [PDF]

, 2021
Alen Zabotti, Orazio De Lucia, Garifallia Sakellariou, Alberto Batticciotto, Gilberto Cincinelli, Ivan Giovannini, Luca Idolazzi, Gabriella Maioli, Ilaria Tinazzi, Daniel Aletaha, Salvatore De Vita, Antonio Marchesoni, Josef S Smolen, Annamaria Iagnocco, Dennis McGonagle, Roberto Caporali   +15 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A Systematic Approach to Systematic Reviews [PDF]

AORN Journal, 2022
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Regarding: “The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial”

Journal of Translational Medicine, 2021
Takeshi Nakata, Takashi Ariie, Shunsuke Taito   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

How to do a systematic review [PDF]

, 2018
Alex Pollock, Banks JL, Barnett-Page E, Barnett-Page E, Bastian H, Berge E, Bobath B, Boers M, Boger EJ, Booth A, Booth A, Borah R, Brazzelli M, Cahill LS, Carr JH, Chalmers I, Chalmers I, Craig P, Davies PM, Deeks JJ, Dixon-Woods M, Eivind Berge, Fain JA, Feigin VL, Ganann R, Garner P, Glasziou P, Gotzsche PC, Gough D, Gough D, Gough D, Green BN, Greenwood N, Grimshaw J, Guyatt GH, Guyatt GH, Harden A, Higgins JPT, Hoffmann TC, Hoffmann TC, Joanna Briggs Institute, Kastner M, Katrak P, Kirkham JJ, Kreis J, Langhorne P, Lees R, Levac D, Moher D, Moher D, Moher D, Morley RF, Pendlebury ST, Peoples H, PLoS Medicine Editors, Pollock A, Pollock A, Pollock A, Pollock A, Rathbone J, Riva JJ, Rowat A, Sackett DL, Santisteban L, Saunders DH, Silagy CA, Snilstveit B, Stroke Unit Trialists Collaboration, Stroup DF, Thomas J, Tong A, Tyson SF, Tyson SF, Vickrey BG, Waddington H, Wardlaw JM, Weir MC, Whiting PF, Wildridge V, Williamson PR, Wong G, Yaffe J   +81 more
core   +1 more source