Results 61 to 70 of about 1,302,638 (249)

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

Journal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah, Helia Mojtabavi, Atefeh Behkar, Arash Heidari, Atra Ajdari, Zoha Shaka, Seyed Vahid Mousavi, Negar Firoozeh, Abbas Tafakhori, Nima Rezaei   +9 more
doaj   +1 more source

A scientometric analysis of research trends, visualization, and emerging patterns in canine olfactory detection for cancer [PDF]

Veterinary World
Background and Aim: Dogs can detect specific cancer odors with their exceptional sense of smell. This study aimed to conduct a scientometric analysis of canine olfactory detection in oncology, identifying trends, visualizations, and patterns ...
Fran Espinoza-Carhuancho, Franco Mauricio, Cesar Mauricio-Vilchez, Diego Galarza-Valencia, Julia Medina, Josmel Pacheco-Mendoza, Frank Mayta-Tovalino   +6 more
doaj   +1 more source

A model six-month workshop for developing systematic review protocols at teaching hospitals: action research and scholarly productivity

BMC Medical Education, 2021
Background Research engagement contributes to the improvement of patient care. A systematic review is a suitable first scholarly activity because it entails summarization of publicly available data and usually requires neither rigorous ethical review nor
Hiraku Tsujimoto, Yuki Kataoka, Yukihito Sato, Masahiro Banno, Emi Tsujino-Tsujimoto, Yukiyoshi Sumi, Ryuichi Sada, Takashi Fujiwara, Yoichi Ohtake, Junji Kumasawa, Haruki Imura, Yoshinobu Matsuda, Ryuhei So, Tomoko Kagawa, Takashi Yoshioka, Yu Uneno, Hiroyuki Nagano, Mai Akazawa, Takunori Hozumi, Yasushi Tsujimoto   +19 more
doaj   +1 more source

Interventions for physician burnout: A systematic review of systematic reviews

International Journal of Preventive Medicine, 2018
Occupational burnout is a common syndrome among physicians, and several individual-directed and organization-directed interventions have been implemented to reduce it. Until now, several review studies have tried to identify and introduce the most appropriate interventions.
Simin dokht Kalani, Peyman Adibi, Parviz Azadfallah, Hamidreza Oreyzi   +3 more
openaire   +4 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Medicinal Plants Used in Treatment of Noninfectious Skin Diseases: A Systematic Review

Journal of Medicinal Plants, 2012
The use of medicinal plants and plant active constituents in the treatment of skin diseases is very common. Here, primarily the clinical trials concerning the use of medicinal plants and plant active constituents in the treatment of noninfectious skin ...
S Kianbakht
doaj  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Systematic review of the effectiveness of standalone passive countermeasures on microgravity-induced physiologic deconditioning

npj Microgravity
A systematic review of literature was conducted to evaluate the effectiveness of passive countermeasures in ameliorating the cardiopulmonary and musculoskeletal effects of gravitational unloading on humans during spaceflight.
Syed Shozab Ahmed, Nandu Goswami, Adam Sirek, David Andrew Green, Andrew Winnard, Leonie Fiebig, Tobias Weber   +6 more
doaj   +1 more source