Results 61 to 70 of about 2,078,039 (268)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Two physiotherapists, one librarian and a systematic literature review: Collaboration in action

, 2006
Aim: This paper explores the processes of collaboration between a librarian and two academic physiotherapists working on a systematic review jointly funded by the University of the West of England (UWE), Bristol, and the Royal National Hospital for ...
Swinkels, Annette, Hall, Jane, Briddon, Jason   +2 more
core   +1 more source

A systematic review of systematic reviews on blended learning: Trends, gaps and future directions

, 2022
Blended Learning (BL) is one of the most used methods in education to promote active learning and enhance students’ learning outcomes. Although BL has existed for over a decade, there are still several challenges associated with it.
Tlili, Ahmed, Ashraf, M.A, Huang, Ronghuai, Denden, Mouna, Liu, J., Burgos, Daniel, Yang, M., Zhang, Y.   +7 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Systematic reviews of diagnostic tests in cancer: review of methods and reporting

, 2006
Objectives To assess the methods and reporting of systematic reviews of diagnostic tests. Data sources Systematic searches of Medline, Embase, and five other databases identified reviews of tests used in patients with cancer.
Hopewell, S, Cornelius, V, Halligan, S, Deeks, Jonathan J., Deeks, Jonathan, Altman, Douglas G, Deeks, Jonathan J, Halligan, Steve, Halligan, S., Hopewell, S., Altman, D.G., Cornelius, V., Hopewell, Sally, Altman, DG, Cornelius, Victoria, Altman, Douglas G., Deeks, J.J., Mallett, S, Deeks, JJ, Mallett, S., Mallett, Susan   +20 more
core   +1 more source

Systematic Review of Tumor Segmentation Strategies for Bone Metastases

, 2023
Purpose: To investigate the segmentation approaches for bone metastases in differentiating benign from malignant bone lesions and characterizing malignant bone lesions.
Matthew Field, Iromi R. Paranavithana, David Stirling, Montserrat Ros   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A systematic review: Sinomenine

Heliyon
Sinomenine (SIN), an alkaloid derived from the traditional Chinese medicine, Caulis Sinomenii, has been used as an anti-inflammatory drug in China for over 30 years. With the continuous increase in research on the pharmacological mechanism of SIN, it has been found that, in addition to the typical rheumatoid arthritis (RA) treatment, SIN can be used as
Shan Jiang, Shuang Li, Siyuan Pang, Mei Liu, Huifeng Sun, Ning Zhang, Jianxin Liu   +6 more
openaire   +3 more sources

Text Messaging in Cancer-Supportive Care: A Systematic Review

, 2021
The global cancer disease burden is substantial, resulting in increased economic and clinical strain on our healthcare systems. A proposed solution is text-based communication, which can be used for cancer-supportive care.
Bishal Gyawali, Isobel Sharpe, Siddhartha Srivastava, Meghan Bowman, Don Thiwanka Wijeratne, Matthew Jalink   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source