Results 121 to 130 of about 2,543,955 (363)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

What pedagogical approaches can effectively include children with special educational needs in mainstream classrooms? The interactions of peers, teachers and support staff [PDF]

open access: yes, 2005
This paper addresses issues raised by the systematic literature review process. The authors are currently examining the literature on the pedagogy of mainstream teachers and support staff that effectively include children with special educational needs ...
Hall, Kathy, Rix, Jonathan
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The development of QUADAS : a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews [PDF]

open access: yes, 2003
BACKGROUND: In the era of evidence based medicine, with systematic reviews as its cornerstone, adequate quality assessment tools should be available.
Anne WS Rutjes   +14 more
core   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Health, not weight loss, focused programmes versus conventional weight loss programmes for cardiovascular risk factors (Protocol) [PDF]

open access: yes, 2014
This is the protocol for a review and there is no abstract. The objectives are as follows: The aim of this review is to compare the effects of Health, not weight loss, focussed (HNWL) programmes with those of conventional weight loss (CWL) programmes on ...
Farley, A..C.   +5 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Bibliometric Analysis of Librarian Involvement in Systematic Reviews at the University of Alberta

open access: yesJournal of the Canadian Health Libraries Association
Introduction - It is well documented that librarian involvement in systematic reviews generally increases quality of reporting and the review overall.
Janice Y. Kung, Megan R. Kennedy
doaj   +1 more source

Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria- a systematic review for the EAACI Biologicals Guidelines [PDF]

open access: gold, 2020
Ioana Agache   +25 more
openalex   +1 more source

Home - About - Disclaimer - Privacy