Results 161 to 170 of about 553,744 (267)

Telehealth Interventions in Pharmacy Practice: Systematic Review of Reviews and Recommendations. [PDF]

J Med Internet Res
Chong RLK, Chan ASE, Chua CMS, Lai YF, Lai YF.   +4 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A systematic review of reviews on comprehensive community initiatives to prevent or reduce alcohol and other drug harms. [PDF]

Addiction
Gates PJ, Zocco AC, Farnbach S.
europepmc   +1 more source

Relationships between nursing leadership and organizational, staff and patient outcomes: A systematic review of reviews. [PDF]

Nurs Open, 2023
Hult M, Terkamo-Moisio A, Kaakinen P, Karki S, Nurmeksela A, Palonen M, Peltonen LM, Häggman-Laitila A.   +7 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Patient-clinician communication in longitudinal care settings about adverse childhood experiences (ACEs) and adult traumas: A systematic review of reviews. [PDF]

Patient Educ Couns
Hargrave-Bouagnon AS, Escober J, Talavera G, Bernard-Pearl D, Cohen BE, Schillinger D.   +5 more
europepmc   +1 more source

Physical Activity and Depression and Anxiety Disorders: A Systematic Review of Reviews and Assessment of Causality. [PDF]

AJPM Focus, 2023
Wanjau MN, Möller H, Haigh F, Milat A, Hayek R, Lucas P, Veerman JL.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evaluating the evidence: a systematic review of reviews of the effectiveness and safety of digital interventions for ADHD. [PDF]

BMC Psychiatry
Gabarron E, Denecke K, Lopez-Campos G.
europepmc   +1 more source