Results 211 to 220 of about 1,970,365 (311)

Relationships between nursing leadership and organizational, staff and patient outcomes: A systematic review of reviews. [PDF]

Nurs Open, 2023
Hult M, Terkamo-Moisio A, Kaakinen P, Karki S, Nurmeksela A, Palonen M, Peltonen LM, Häggman-Laitila A.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Physical Activity and Depression and Anxiety Disorders: A Systematic Review of Reviews and Assessment of Causality. [PDF]

AJPM Focus, 2023
Wanjau MN, Möller H, Haigh F, Milat A, Hayek R, Lucas P, Veerman JL.   +6 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Evaluating the evidence: a systematic review of reviews of the effectiveness and safety of digital interventions for ADHD. [PDF]

BMC Psychiatry
Gabarron E, Denecke K, Lopez-Campos G.
europepmc   +1 more source

Barriers and facilitators of domain-specific physical activity: a systematic review of reviews. [PDF]

BMC Public Health, 2022
Garcia L, Mendonça G, Benedetti TRB, Borges LJ, Streit IA, Christofoletti M, Silva-Júnior FLE, Papini CB, Binotto MA.   +8 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Interventions Addressing Health Literacy in Cancer Care: A Systematic Review of Reviews. [PDF]

Int J Environ Res Public Health
Jeitani C, Van den Broucke S, Leemans C.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Addressing health service equity through telehealth: A systematic review of reviews. [PDF]

Digit Health
Wang S, von Huben A, Sivaprakash PP, Saurman E, Norris S, Wilson A.   +5 more
europepmc   +1 more source