Results 1 to 10 of about 552,583 (264)

High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2021
Background: Early diagnosis of acute myocardial infarction is important, but only 20% of emergency admissions for chest pain will actually have an acute myocardial infarction.
Marie Westwood   +9 more
doaj   +1 more source

A systematic review of clinical effectiveness and safety for historical and current treatment options for metachromatic leukodystrophy in children, including atidarsagene autotemcel

open access: yesOrphanet Journal of Rare Diseases, 2023
Objective To understand the benefit-risk profile for historical and current treatments for MLD. Methods A systematic review was conducted on the effectiveness, safety, and costs of MLD treatments: allogeneic haematopoietic stem cell transplantation (HSCT)
Nigel Armstrong   +3 more
doaj   +1 more source

Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2020
Background: There have been no licensed treatment options in the UK for treating thrombocytopenia in people with chronic liver disease requiring surgery.
Nigel Armstrong   +15 more
doaj   +1 more source

Efficacy of antimalarial herbal medicines used by communities in malaria affected regions globally: a protocol for systematic review and evidence and gap map

open access: yesBMJ Open, 2023
Introduction With the rising resistance to artemisinin-based combination treatments, there is a need to hasten the discovery and development of newer antimalarial agents. Herbal medicines are key for the development of novel drugs.
Nakalembe Loyce   +5 more
doaj   +1 more source

Registering systematic reviews [PDF]

open access: yesCanadian Medical Association Journal, 2009
More than 5500 systematic reviews, at various stages of completion, are currently available in the Cochrane Library ([www.cochrane.org][1]) and 9000 systematic reviews are critically appraised for validity in the Database of Abstracts of Reviews of Effectiveness, or DARE ([www.crd.york.ac.uk][2]).
Sharon, Straus, David, Moher
openaire   +2 more sources

Otomyiasis: Systematic Review [PDF]

open access: yesInternational Archives of Otorhinolaryngology, 2018
Introduction Myiasis is a disease caused by fly larvae that grow in the tissues of animals and humans. It can cause a variety of local symptoms, like erythema or pain, depending on its location, and generalized symptomatology, such as fever and malaise.
Rodríguez-Ruiz,María Teresa   +4 more
openaire   +5 more sources

The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males.
S. Ryder   +7 more
doaj   +1 more source

Systematic reviews

open access: yesNursing Standard, 2015
Despite the increasing popularity of systematic reviews, there remains a need to ensure that they are conducted rigorously and provide an objective critical summary of research findings. The strength of a systematic review is its rigorous methodological approach to interrogating a body of literature. Both authors and readers should be familiar with the
Halcomb, Elizabeth J, Fernandez, Ritin S
openaire   +4 more sources

Iridoschisis—A Systematic Review [PDF]

open access: yesJournal of Clinical Medicine, 2020
Iridoschisis is a rare condition defined as a separation of the anterior iris stroma from the posterior stroma and muscle layers. In this paper, we review current data about the epidemiology, pathophysiology, clinical characteristics and differential diagnoses of this condition and discuss the specificity of surgical treatment of concomitant ocular ...
Barbara Pieklarz   +5 more
openaire   +3 more sources

SeHCAT (tauroselcholic [75selenium] acid) for the investigation of bile acid diarrhoea in adults: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2022
Background: Tauroselcholic [75selenium] acid (SeHCAT™) (GE Healthcare, Chicago, IL, USA) is a radiopharmaceutical that may be useful in diagnosing bile acid diarrhoea.
Marie Westwood   +7 more
doaj   +1 more source

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