Results 151 to 160 of about 3,583,013 (282)

Open Science Practices in Systematic Reviews From 2014 to 2024: A Cohort Study of 300 Systematic Reviews. [PDF]

Cochrane Evid Synth Methods
Färnqvist K, Karlsson P, Wachtmeister V, Vallance P, Sinervo E.   +4 more
europepmc   +1 more source

Systematic review of systematic reviews

A systematic review of systematic reviews of policy measures and interventions designed to prevent overweight and obesity among children and adolescents will be provided.
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

How should retrospectively registered protocols be interpreted in systematic reviews? [PDF]

Syst Rev
Canellas JVDS, Borges FCP.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Prehabilitation in adult cancer patients: an overview of systematic reviews. [PDF]

BMJ Open
Xiong ZY, Fu ZR, Chen JY, Chen T, Yang S.   +4 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Enhancing Interpretability of AI Performance Metrics in Rheumatology Systematic Reviews. [PDF]

Int J Rheum Dis
Zhao S, Du Y.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Mental health disparities in LGBTQIA+ populations: an umbrella review of systematic reviews and meta-analyses. [PDF]

World Psychiatry
Oliva V, Radua J, De Prisco M, Cerioli M, Bort M, Possidente C, Bracco L, Anmella G, Salazar de Pablo G, Fico G, Vieta E.   +10 more
europepmc   +1 more source