Results 51 to 60 of about 14,049,576 (343)

Ivacaftor for the treatment of patients with cystic fibrosis and the G551D mutation: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2014
Background: Ivacaftor (Kalydeco®, Vertex Pharmaceuticals) is the first of a new class of drugs that target the underlying protein defect in cystic fibrosis (CF).
Penny Whiting   +9 more
doaj   +1 more source

Response to “Phrase truncation in PubMed searches”

open access: yesJournal of the Medical Library Association, 2017
Response to Shanman R. Phrase truncation in PubMed searches [letter to the editor]. J Med Libr Assoc. 2017 Oct;105(4). DOI: http://dx.doi.org/10.5195/jmla.2017.252. Comment on Duffy S, de Kock S, Misso K, Noake C, Ross J, Stirk L. Supplementary searches
Steven Duffy   +5 more
doaj   +1 more source

Overview of Differences and Similarities of Published Mixed Treatment Comparisons on Pharmaceutical Interventions for Multiple Sclerosis

open access: yesNeurology and Therapy, 2020
Introduction Mixed treatment comparisons (MTCs) are increasingly important in the assessment of the benefit–risk profile of pharmaceutical treatments for relapsing–remitting multiple sclerosis (RRMS). Interpretation of MTCs requires a clear understanding
Maria Pia Sormani   +8 more
doaj   +1 more source

Which academic search systems are suitable for systematic reviews or meta‐analyses? Evaluating retrieval qualities of Google Scholar, PubMed, and 26 other resources

open access: yesResearch Synthesis Methods, 2020
Rigorous evidence identification is essential for systematic reviews and meta‐analyses (evidence syntheses) because the sample selection of relevant studies determines a review's outcome, validity, and explanatory power.
Michael Gusenbauer, Neal R Haddaway
semanticscholar   +1 more source

A systematic review of reviews of interventions to promote mental health and prevent mental health problems in children and young people [PDF]

open access: yes, 2007
Background: There is a growing policy imperative to promote positive mental health as well as preventing the development of mental health problems in children.
Barlow, Jane   +4 more
core   +1 more source

Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2015
Background: Determination of the presence or absence of bacterial infection is important to guide appropriate therapy and reduce antibiotic exposure.
Marie Westwood   +9 more
doaj   +1 more source

A Systematic Review and Mixed Treatment Comparison of Pharmaceutical Interventions for Multiple Sclerosis

open access: yesNeurology and Therapy, 2020
Background Since 2010, 27 mixed-treatment comparisons (MTCs) of disease-modifying therapies (DMTs) for multiple sclerosis have been published. However, there has been continued evolution in the field of MTCs.
Gavin Giovannoni   +8 more
doaj   +1 more source

The impact of eHealth on the quality and safety of health care : a systematic overview [PDF]

open access: yes, 2010
There is considerable international interest in exploiting the potential of digital solutions to enhance the quality and safety of health care. Implementations of transformative eHealth technologies are underway globally, often at very considerable cost.
Anandan, Chantelle   +10 more
core   +6 more sources

Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2015
Background: Patients with substantive bleeding usually require transfusion and/or (re-)operation. Red blood cell (RBC) transfusion is independently associated with a greater risk of infection, morbidity, increased hospital stay and mortality.
Penny Whiting   +9 more
doaj   +1 more source

Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis CHEST Guideline and Expert Panel Report [PDF]

open access: yes, 2017
BACKGROUND: Wet or productive cough is common in children with chronic cough. We formulated recommendations based on systematic reviews related to the management of chronic wet cough in children (aged METHODS: We used the CHEST expert cough panel\u27s ...
Chang, Anne B.   +7 more
core   +2 more sources

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