Results 241 to 250 of about 1,783,022 (384)

Involvement of medical writers in the development of health economic and outcomes research publications in inflammatory bowel disease - a systematic literature review [PDF]

, 2017
Shailesh Y. Desai, Gina D’Angelo, Antonia Panayi, Slávka Baróniková, Gemma Carter, Obaro Evuarherhe, Kim Wager, Richard White   +7 more
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Near-field and far-field exposures to radiofrequency electromagnetic fields and cancer risks in humans: a protocol for an umbrella review of epidemiological studies. [PDF]

Syst Rev
Ziegler JL, Lagorio S, Mattsson MO, Zeni O, Bolte J, Ledent M, Velghe M, Stam R, Rijs K, Deltour I, Dolatkhah R, Wollschläger D, Petroulakis N, Ortolano LC, Baaken D.   +14 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Investigations for Bronchiolitis in Infants: An Overview of Reviews and Systematic Review of Primary Studies. [PDF]

Pediatr Pulmonol
Loveys K, Borland ML, Oakley E, Babl FE, Cotterell E, Harrison G, Haskell L, O'Brien S, Tavender EJ, Wilson CL, Dalziel SR, Paediatric Research in Emergency Departments International Collaborative (PREDICT) network.   +11 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Methodological Quality of Umbrella Reviews in Paediatric Dentistry: A Cross-Sectional Study. [PDF]

Int Dent J
Gopinath VK, Govindaraju L, Pulikkotil SJ, Narasimhan S, Shetty RM, Faggion CM, Dummer PMH, Nagendrababu V.   +7 more
europepmc   +1 more source

An introduction to systematic reviews and meta-analysis: A workshop report on promoting evidence based medical practice through capacity building in research synthesis

, 2011
Lawrence Mbuagbaw, Charles Shey Wiysonge, DS Nsagha, Pierre Ongolo‐Zogo, Tomás Pantoja   +4 more
openalex   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

What Does Indian Dermatology Online Journal Expect in a Review Article? [PDF]

Indian Dermatol Online J
Grover C, De D.
europepmc   +1 more source