Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Testing Capital Asset Pricing Model: Empirical Evidences from Indian Equity Market [PDF]
Eurasian Journal of Business and Economics, 2010 The present study examines the Capital Asset Pricing Model (CAPM) for the Indian stock market using monthly stock returns from 278 companies of BSE 500 Index listed on the Bombay stock exchange for the period of January 1996 to December 2009.
Kapil CHOUDHARY, Sakshi CHOUDHARY
doaj
Risk Transmission of Trade Price Fluctuations from a Nickel Chain Perspective: Based on Systematic Risk Entropy and Granger Causality Networks. [PDF]
Entropy (Basel), 2022 Zhou X +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Systematic Property Risk: Quantifying UK Property Betas 1983-2005 [PDF]
The increased frequency in reporting UK property performance figures, coupled with the acceptance of the IPD database as the market standard, has enabled property to be analysed on a comparable level with other more frequently traded assets.
George Matysiak, Alan Gardner
core
HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention. [PDF]
, 2010 BACKGROUND: The human immunodeficiency virus (HIV) infectiousness of anal intercourse (AI) has not been systematically reviewed, despite its role driving HIV epidemics among men who have sex with men (MSM) and its potential contribution to heterosexual ...
Marie-Claude Boily +9 more
core +1 more source
Manajemen dan Bisnis, 2017 This study aimed to examine the effect of capital structure, growth opportunity, and the systematic risk of the capital structure and the effect of capital structure on firm value.
Nurfitri Desliniati, Didi Sundiman
doaj +1 more source
Improving Risk Assessment in Clinical Trials: Toward a Systematic Risk-Based Monitoring Approach. [PDF]
Curr Ther Res Clin Exp, 2021 Fneish F, Schaarschmidt F, Fortwengel G.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer : a systematic review and overview of reviews [PDF]
, 2013 Background: Prophylactic aspirin has been considered to be beneficial in reducing the risks of heart disease and cancer. However, potential benefits must be balanced against the possible harm from side effects, such as bleeding and gastrointestinal (GI ...
Gurung, T. +19 more
core +1 more source