Results 131 to 140 of about 3,732,762 (303)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Risk-based screening programmes for cancer diagnosis: A systematic review with narrative synthesis

Annals, Academy of Medicine, Singapore
Introduction: Risk-based screening (RBS) has emerged as a promising alternative to age-based cancer screening. However, evidence regarding real-world implementation outcomes remains fragmented.
Yong Yi Tan, Sara Tasnim, Mohammad Fahmy Bin Fadzil, Xin Rong Ng, Sabrina KW Wong, Jo-Anne Elizabeth Manski-Nankervis, Joseph Jao-Yiu Sung, Joanne Ngeow   +7 more
doaj   +1 more source

[Systematic risk management for a planned gas shutdown in the high-care facility of a university hospital]. [PDF]

Anaesthesiologie, 2023
Heller AR, Eberlein-Gonska M, Held HC, Koch T.   +3 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Performance Analysis of a Collateralized Fund Obligation (CFO) Equity Tranche [PDF]

This article examines the performance of the junior tranche of a Collateralized Fund Obligation (CFO), i.e. the residual claim (equity) on a securitized portfolio of hedge funds.
Georges Dionne, Nicolas Papageorgiou, Shady Aboul-Enein   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

ANALISIS FAKTOR FUNDAMENTAL DAN RISIKO SISTEMATIK TERHADAP HARGA SAHAM PROPERTI DI BEJ

Jurnal Akuntansi dan Keuangan, 2003
Property was one of sectors that suffer very much during economic crisis. This caused the securities property price decrease on stock exchange. The objective of this research is to understand fundamental factors and systematic risk that influence ...
Imelda Wijiyanti, Njo Anastasia, Yanny Widiastuty Gunawan   +2 more
doaj  

A generalized method for detecting abnormal returns and changes in systematic risk [PDF]

The authors generalize traditional event-study techniques to allow for event-induced parameter shifts, shifting variances, and firm-specific event periods.
Ken B. Cyree, Ramon P. DeGennaro
core  

Systematic Development of Trans-Theoretically Based Behavioral Risk Management Programs [PDF]

, 1993
The authors explain the development and use of a behavioral Risk management strategy. It is designed for developing interventions to change behaviors, e.g., to lower the Risk of AIDS.
Cole, Galen E., Holtgrave, David R., Rios, Nilka M.   +2 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source