Results 231 to 240 of about 13,028,724 (400)
Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn +11 morewiley +1 more sourceInvestor Expectations and Systematic Risk [PDF]
This study refines the estimation of beta risk within the Capital Asset Pricing Model (CAPM) framework. Evidence is provided that the link between ex-ante risk and ex-post returns is strengthened by more accurately reflecting the formation of investor ...Adam Clements, Michael E. Drewcore Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski +17 morewiley +1 more sourceGlobal, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
The Lancet, 2018 J. Stanaway, A. Afshin, E. Gakidou, Stephen S. Lim, D. Abate, K. H. Abate, C. Abbafati, N. Abbasi, H. Abbastabar, F. Abd-Allah, Jemal Abdela, A. Abdelalim, Ibrahim Abdollahpour, R. Abdulkader, Molla Abebe, Zegeye Abebe, S. Abera, O. Abil, H. Abraha, Aklilu Abrham, L. Abu-Raddad, Niveen M. E. Abu-Rmeileh, Manfred Mario Kokou Accrombessi, Dilaram Acharya, Pawan Acharya, A. A. Adamu, A. Adane, O. Adebayo, R. Adedoyin, Victor Adekanmbi, Z. Ademi, O. Adetokunboh, Mina G. Adib, Amha Admasie, J. Adsuar, K. Afanvi, M. Afarideh, Gina Agarwal, Anju Aggarwal, S. Aghayan, Anurag Agrawal, S. Agrawal, A. Ahmadi, Mehdi Ahmadi, H. Ahmadieh, M. Ahmed, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Mohammad Esmaeil Akbari, T. Akinyemiju, N. Akseer, Z. Al-Aly, A. Al-Eyadhy, H. Al-Mekhlafi, Fares Alahdab, K. Alam, Samiah Alam, Tahiya Alam, Alaa Alashi, S. Alavian, K. Alene, Komal Ali, Syed Mustafa Ali, M. Alijanzadeh, Reza Alizadeh-Navaei, S. Aljunid, A. Alkerwi, François Alla, U. Alsharif, K. Altirkawi, N. Alvis-Guzmán, Azmeraw T. Amare, W. Ammar, N. Anber, Jason A Anderson, C. Andrei, S. Androudi, Megbaru Debalkie Animut, Mina Anjomshoa, Mustafa Geleto Ansha, Josep M. Antó, C. Antonio, P. Anwari, L. Appiah, Seth Christopher Yaw Appiah, J. Arabloo, O. Aremu, J. Ärnlöv, A. Artaman, K. Aryal, H. Asayesh, Z. Ataro, M. Ausloos, Euripide Avokpaho, A. Awasthi, B. P. Ayala Quintanilla, R. Ayer, T. B. Ayuk, P. Azzopardi, A. Babazadeh, H. Badali, A. Badawi, Kalpana Balakrishnan, A. G. Bali, Kylie Ball, S. Ballew, Maciej Banach, J. Banoub, A. Barać, S. Barker-Collo, T. Bärnighausen, L. Barrero, Sanjay Basu, B. Baune, S. Bazargan-Hejazi, Neeraj Bedi, Ettore Beghi, Masoud Behzadifar, M. Behzadifar, Y. Béjot, B. B. Bekele, Eyasu Tamru Bekru, Ezra Belay, Yihalem Abebe Belay, Morag Bell, A. Bello, Derrick A. Bennett, I. Benseñor, Gilles Bergeron, A. Berhane, Eduardo Bernabé, Robert S. Bernstein, M. Beuran, Tina Beyranvand, N. Bhala, Ashish Bhalla, S. Bhattarai, Z. Bhutta, B. Biadgo, Ali Bijani, B. Bikbov, V. Bilano, Nigus Bililign, M. B. Bin Sayeed, D. Bisanzio, Tuhin Biswas, T. Bjørge, B. Blacker, A. Bleyer, R. Borschmann, I. Bou-Orm, S. Boufous, R. Bourne, O. Brady, Michael Brauer, A. Brazinova, N. Breitborde, H. Brenner, A. Briko, Gabrielle Britton, T. Brugha, Rachelle Buchbinder, R. Burnett, Reinhard Busse, Z. Butt, Leah E Cahill, Lucero Cahuana-Hurtado, Ismael Campos-Nonato, Rosario Cárdenas, Giulia Carreras, J. Carrero, F. Carvalho, C. Castañeda-Orjuela, Jacqueline Castillo Rivas, Franz Castro, Ferrán Catalá-López, K. Causey, Kelly M. Cercy, Ester Cerin, Y. Chaiah, Hsing-Yi Chang, Jung-Chen Chang, Kai-Lan Chang, F. Charlson, Aparajita Chattopadhyay, Vijay Kumar Chattu, M. Chee, Ching-Yu Cheng, Adrienne Chew, P. Chiang, Odgerel Chimed-Ochir, K. Chin, Abdulaal Chitheer, J. Choi, Rajiv Chowdhury, H. Christensen, D. Christopher, Sheng-Chia Chung, F. Cicuttini, Massimo Cirillo, Aaron J. Cohen, D. Collado-Mateo, C. Cooper, Owen R. Cooper, J. Coresh, Leslie Cornaby, P. Cortesi, Monica Cortinovis, Megan Costa, Ewerton Cousin, M. Criqui, E. Cromwell, D. Cundiff, A. K. Daba, B. Dachew, A. Dadi, Albertino Damasceno, L. Dandona, R. Dandona, Sarah C. Darby, P. Dargan, A. Daryani, R. Das Gupta, J. D. das Neves, T. Dasa, Aditya Prasad Dash, D. Davițoiu, K. Davletov, Vanessa De la Cruz-Góngora, Fernando Pio De la Hoz, Diego De Leo, Jan‐Walter De Neve, L. Degenhardt, Selina Deiparine, R. Dellavalle, Gebre Teklemariam Demoz, E. Denova-Gutiérrez, Kebede Deribe, Nikolaos Dervenis, Aniruddha Deshpande, D. D. Des Jarlais, Getenet Dessie, G. deVeber, Subhojit Dey, S. Dharmaratne, M. Dhimal, Mesfin Tadese Dinberu, Eric L. Ding, Helen Derara Diro, S. Djalalinia, H. Do, K. Dokova, D. Doku, Kerrie E. Doyle, T. Driscoll, Manisha Dubey, E. Dubljanin, Eyasu Ejeta Duken, B. B. Duncan, A. Durães, Natalie Ebert, H. Ebrahimi, S. Ebrahimpour, D. Edvardsson, Andem Effiong, A. Eggen, C. El Bcheraoui, Z. El-Khatib, I. Elyazar, A. Enayati, A. Endries, Benjamin Er, H. Erskine, S. Eskandarieh, A. Esteghamati, Kara Estep, H. Fakhim, Mahbobeh Faramarzi, Mohammad Fareed, Talha A Farid, C. Farinha, A. Farioli, Andre Faro, M. Farvid, M. Farzaei, Batool Fatima, K. Fay, A. Fazaeli, Valery L. Feigin, A. Feigl, S. Fereshtehnejad, Eduarda Fernandes, João Catalão, Giannina Ferrara, A. Ferrari, Manuela L Ferreira, I. Filip, J. D. Finger, F. Fischer, N. Foigt, Kyle Foreman, Takeshi Fukumoto, N. Fullman, Thomas Fürst, João M. Furtado, Neal D Futran, S. Gall, Silvano Gallus, A. Gamkrelidze, M. Ganji, A. García-Basteiro, William M Gardner, A. Gebre, A. Gebremedhin, Teklu Gebrehiwo Gebremichael, Tilayie Feto Gelano, J. Geleijnse, Y. C. D. Geramo, P. Gething, Kebede Embaye Gezae, Reza Ghadimi, K. Ghadiri, Khalil Ghasemi Falavarjani, Maryam Ghasemi-Kasman, M. Ghimire, Rakesh Ghosh, A. Ghoshal, Simona Giampaoli, P. Gill, Tiffany K. Gill, R. F. Gillum, I. Ginawi, G. Giussani, E. Gnedovskaya, W. Godwin, Srinivas Goli, H. Gómez-Dantés, P. Gona, S. Gopalani, A. Goulart, A. Grada, Morgan E. Grams, Giuseppe Grosso, H. Gugnani, Yuming Guo, Rahul Gupta, R. Gupta, Tanush Gupta, R. A. Gutiérrez, Daniela S. Gutiérrez-Torres, J. Haagsma, T. Habtewold, Vladimir Hachinski, N. Hafezi-Nejad, Tekleberhan B Hagos, Tewodros Tesfa Hailegiyorgis, G. B. Hailu, Arvin Haj-Mirzaian, A. Haj-Mirzaian, R. Hamadeh, S. Hamidi, A. Handal, Graeme J. Hankey, Yuantao Hao, H. Harb, S. Harikrishnan, J. Haro, H. Hassankhani, H. Y. Hassen, Rasmus J. Havmoeller, Caitlin N Hawley, Simon Iain Hay, A. Hedayatizadeh-Omran, B. Heibati, B. Heidari, Mohsen Heidari, D. Hendrie, A. Henok, I. Heredia-Pi, C. Herteliu, F. Heydarpour, Sousan Heydarpour, D. Hibstu, T. Higazi, E. Hilawe, Hans W. Hoek, Howard J Hoffman, M. K. Hole, Enayatollah Homaie Rad, Praveen Hoogar, H. Hosgood, Seyed Mostafa Hosseini, M. Hosseinzadeh, M. Hostiuc, S. Hostiuc, D. Hoy, M. Hsairi, Thomas Hsiao, Guoqing Hu, Howard Hu, John J Emmanuel Huang, Mamusha Hussen, Chantal K Huynh, K. Iburg, Nayu Ikeda, O S Ilesanmi, Usman Iqbal, S. Irvani, C. Irvine, Sheikh Mohammed Shariful Islam, F. Islami, Maria D. Jackson, K. Jacobsen, L. Jahangiry, N. Jahanmehr, Sudhir Kumar Jain, Mihajlo Jakovljevic, S. James, S. Jassal, A. Jayatilleke, P. Jeemon, Ravi Prakash Jha, Vivekanand Jha, John S Ji, J. Jonas, J. Jonnagaddala, Z. Jorjoran Shushtari, Ankur Joshi, J. Jozwiak, M. Jürisson, Zubair Kabir, Amaha Kahsay, Rizwan Kalani, T. Kanchan, Surya Kant, Chittaranjan Kar, Manoochehr Karami, B. Karami Matin, A. Karch, C. Karema, Narges Karimi, Seyed M. Karimi, A. Kasaeian, D. H. Kassa, G. Kassa, T. Kassa, N. Kassebaum, S. Katikireddi, Anil Kaul, Norito Kawakami, Zhila Kazemi, Ali Kazemi Karyani, A. Kefale, P. Keiyoro, Grant Rodgers Kemp, A. Kengne, Andre Keren, C. Kesavachandran, Yousef S. Khader, Behzad Khafaei, M. Khafaie, Alireza Khajavi, Nauman Khalid, I. Khalil, Gulfaraz Khan, M. Khan, Muhammad Ali Khan, Y. Khang, M. Khater, Mohammad Khazaei, Habibolah Khazaie, A. Khoja, A. Khosravi, Mohammad Hossein Khosravi, A. Kiadaliri, Daniel N. Kiirithio, Cho-il Kim, Daniel H. Kim, Young-Eun Kim, Y. Kim, R. Kimokoti, Y. Kinfu, A. Kisa, K. Kissimova-Skarbek, Mika Kivimäki, L. Knibbs, A. Knudsen, S. Kochhar, Y. Kokubo, Tufa Kolola, J. Kopec, S. Kosen, P. Koul, Ai Koyanagi, M. Kravchenko, K. Krishan, Kristopher J. Krohn, H. Kromhout, Barthelemy Kuate Defo +499 moresemanticscholar +1 more sourcePhenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer +9 morewiley +1 more sourceEssays on risk management and systematic risk [PDF]
, 2013 Through the creation of the Financial Stability Board (FSB), G20 members have committed to regulate the financial sector across the globe in order to enhance the resilience of the system. Two important points in this agenda are the regulation of OTC derivatives, such as Credit Default Swaps (CDS) and the regulation of Systemically Important Financial ...openaire +2 more sourcesDammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh +8 morewiley +1 more source
