Results 111 to 120 of about 2,502,850 (290)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Weak Lensing Science, Surveys, and Systematics
11 pages, 9 ...
Das, Sudeep +3 more
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Extraction of the Baryon Acoustic Oscillations (BAO) to percent level accuracy is challenging and demands an understanding of many potential systematic to an accuracy well below 1 per cent, in order ensure that they do not combine significantly when ...
Aubourg, Eric +14 more
core
Integrating automated valuation models (AVMs) with valuation services to meet the needs of UK borrowers, lenders and valuers [PDF]
Lenders traditionally instruct a valuer to conduct a property valuation to support property secured loan decisions. However AVM use for UK residential loan valuations has recently grown rapidly (CML, 2007) raising questions about how the UK valuers ...
Downie, Mary-Lou, Robson, Gill
core
Robust Control Methods a Systematic Survey [PDF]
The paper addresses the problem how to recognize a level of robust controller design and is aimed show the difficulties of implementation for practical use. In the first part of paper we introduce the survey of robust controller design for SISO systems with generalization design procedure for structured and unstructured uncertainties.
openaire +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Periodic minimal surfaces of cubic symmetry [PDF]
A survey of cubic minimal surfaces is presented, based on the concept of fundamental surface patches and their relation to the asymmetric units of the space groups.
Lord, Eric A., Mackay, Alan L.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

