In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Corrigendum to methodological approaches for developing, reporting, and assessing evidence-based clinical practice guidelines: a systematic survey [Journal of Clinical Epidemiology 146 (2022) 77-85] [PDF]
Xiaomei Yao +11 more
openalex +1 more source
A Systematic Survey of Prompt Engineering on Vision-Language Foundation Models
Jindong Gu +9 more
semanticscholar +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Methods to perform systematic reviews of patient preferences: a literature survey [PDF]
Tsung Yu +2 more
openalex +1 more source
A systematic search for massive young stars in the Galaxy - the RMS survey [PDF]
We have selected red MSX sources (RMS) that have the colours of massive young stellar objects (MYSOs). Our aim is to generate a large, systematically selected sample to address questions such as their luminosity function, lifetimes, clustering and ...
Busfield, AL +5 more
core +2 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Extraction of the Baryon Acoustic Oscillations (BAO) to percent level accuracy is challenging and demands an understanding of many potential systematic to an accuracy well below 1 per cent, in order ensure that they do not combine significantly when ...
Aubourg, Eric +14 more
core
A systematic survey on multimodal emotion recognition using learning algorithms
Naveed Ahmed, Z. Aghbari, S. Girija
semanticscholar +1 more source
Weak Lensing Science, Surveys, and Systematics
11 pages, 9 ...
Das, Sudeep +3 more
openaire +2 more sources

