AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Quantitative abundance and distribution data from the first systematic survey of alien invasive plants in the Xiaoxing'an Mountains, China (2022-2023). [PDF]
Zhang Y, He Z, Dong X, Mu L, Wang H.
europepmc +1 more source
How oral health care organizations formulate actionable statements to inform practice and policy: A protocol for a systematic survey. [PDF]
Verdugo-Paiva F +5 more
europepmc +1 more source
Room for improvement? A survey of the methods used in systematic reviews of adverse effects [PDF]
Su Golder +2 more
openalex +1 more source
Protocol registration issues of systematic review and meta-analysis studies: a survey of global researchers [PDF]
Gehad Mohamed Tawfik +17 more
openalex +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Absence of Host-Specific Hemotropic Mycoplasmas in Horses and Donkeys from Croatia: First Systematic Survey in Southeastern Europe. [PDF]
Konstantinović N +14 more
europepmc +1 more source
COVID-19 retracted publications on retraction watch: A systematic survey of their pre-prints and citations. [PDF]
Syed Z, Syed F, Thabane L, Rodrigues M.
europepmc +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

