Results 131 to 140 of about 3,708,184 (376)

Morphological redescription and molecular phylogeny of a little-known hypotrichous ciliate, Cyrtohymena torrenticola (Šrámek-Hušek, 1957) Foissner, 1989 (Ciliophora, Oxytrichidae) from Baiyangdian Lake, China

open access: yesActa Protozoologica
The present study provides a detailed redescription of the very little-known oxytrichid ciliate, Cyrtohymena torrenticola, collected from Baiyangdian Lake in northern China.
Bowen Zhang   +7 more
doaj   +1 more source

Strong in combination: Polyphasic approach enhances arguments for cold‐assigned cyanobacterial endemism

open access: yesMicrobiologyOpen, 2019
Cyanobacteria of biological soil crusts (BSCs) represent an important part of circumpolar and Alpine ecosystems, serve as indicators for ecological condition and climate change, and function as ecosystem engineers by soil stabilization or carbon and ...
Patrick Jung   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Effects of water flow and ocean acidification on oxygen and pH gradients in coral boundary layer

open access: yesScientific Reports
Reef-building corals live in highly hydrodynamic environments, where water flow largely controls the complex chemical microenvironments surrounding them—the concentration boundary layer (CBL).
Catarina P. P. Martins   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Systematic reviews [PDF]

open access: yesAge and Ageing, 2001
D J, Stott, M, Barber
openaire   +2 more sources

Systematic reviews need systematic searchers.

open access: yesJournal of the Medical Library Association : JMLA, 2005
This paper will provide a description of the methods, skills, and knowledge of expert searchers working on systematic review teams.Systematic reviews and meta-analyses are very important to health care practitioners, who need to keep abreast of the medical literature and make informed decisions.
Jessie, McGowan, Margaret, Sampson
openaire   +1 more source

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