Results 121 to 130 of about 372,756 (303)

Individual Shrimp Rearing Increases the Power of Experimental Trials

open access: yesAquaculture Journal
Comparable and reproducible research is needed to improve Pacific white shrimp (PWS) aquaculture. These experiments typically involve before-and-after measurements of the same individual for paired statistical testing.
Thomas Wilke   +4 more
doaj   +1 more source

Systematic reviews [PDF]

open access: yesAge and Ageing, 2001
D J, Stott, M, Barber
openaire   +2 more sources

Systematic reviews need systematic searchers.

open access: yesJournal of the Medical Library Association : JMLA, 2005
This paper will provide a description of the methods, skills, and knowledge of expert searchers working on systematic review teams.Systematic reviews and meta-analyses are very important to health care practitioners, who need to keep abreast of the medical literature and make informed decisions.
Jessie, McGowan, Margaret, Sampson
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

MdSVWC1, a new pattern recognition receptor triggers multiple defense mechanisms against invading bacteria in Musca domestica

open access: yesBMC Biology
Background Single-domain von Willebrand factor type C (SVWC) constitute a protein family predominantly identified in arthropods, characterized by a SVWC domain and involved in diverse physiological processes such as host defense, stress resistance, and ...
Ting Tang   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Systematics of Beringian threespine sticklebacks [PDF]

open access: yes, 2000
Thesis (M.S.) University of Alaska Fairbanks, 2000In Pleistocene Beringia, large-scale glaciations exposed high latitude species to variable environmental conditions that created disjunct populations of terrestrial and marine species.
Chythlook, John S.
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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