Results 121 to 130 of about 123,080 (305)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Twin Cities ramp meter evaluation : executive summary [PDF]

open access: yes
This report details the results of a study on the traffic flow and safety impacts of ramp metering. The study served two important public purposes. 1. It thoroughly documented the benefits resulting from ramp metering to traffic operations and related ...
Cambridge Systematics
core  

Rhenium-osmium geochronology and geochemistry of ancient lacustrine sedimentary and petroleum systems [PDF]

open access: yes, 2013
The Re-Os geochronometer is a valuable tool able to provide precise depositional ages of marine organic-rich sedimentary rocks as well as the generation age of hydrocarbons. In addition, Os isotopes afford vital insights into seawater Os fluctuations and
CUMMING, VIVIEN,MARY
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Revision and Phylogenetic Systematics of the Neotropical Ceratomerinae (Diptera: Empidoidea: Brachystomatidae)

open access: yes, 2010
Revision and Phylogenetic Systematics of the Neotropical Ceratomerinae (Diptera: Empidoidea: Brachystomatidae) A preliminary phylogeny of the genera and species groups of the Ceratomerinae is presented, with a discussion of the generic concept of ...

core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Unravelling the algae: the past, present and future of algae systematics

open access: yes, 2007
Systematics Association Special Volume ...
Evans, K.M., Mann, David G.
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

"Systematic" [PDF]

open access: yesThe Computer Journal, 1966
openaire   +1 more source

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