Results 71 to 80 of about 372,756 (303)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Emission-line Stacking of 21 cm Intensity Maps with MeerKLASS: Inference Pipeline and Application to the L-band Deep-field Data

The Astrophysical Journal Supplement Series
We present a novel analysis of observational systematics through the emission-line stacking of the MeerKLASS L -band deep-field intensity maps, following the detection in MeerKLASS Collaboration et al.
Zhaoting Chen, Steven Cunnington, Alkistis Pourtsidou, Laura Wolz, Marta Spinelli, José Luis Bernal, Matilde Barberi-Squarotti, Stefano Camera, Isabella P. Carucci, José Fonseca, Keith Grainge, Melis O. Irfan, Mario G. Santos, Jingying Wang, (MeerKLASS Collaboration)   +14 more
doaj   +1 more source

Systematic effects on dark energy from 3D weak shear

, 2008
We present an investigation into the potential effect of systematics inherent in multi-band wide field surveys on the dark energy equation of state determination for two 3D weak lensing methods. The weak lensing methods are a geometric shear-ratio method
A. F. Heavens, A. N. Taylor, Abdalla, Adelman-McCarthy, Benitez, Bernstein, Blake, Bolzonella, Bridle, Brown, Castro, Catelan, Chang, Chevallier, Collister, Cooray, Crittenden, Edmondson, Fisher, Heavens, Heavens, Heavens, Heymans, Heymans, Heymans, Hirata, Hu, Huterer, Huterer, Ishak, Jain, Jungman, Kaiser, King, King, Kitching, Kitching, Kitching, Lima, Linder, Ma, Mandelbaum, Massey, Miller, Munshi, Peacock, Refregier, Rudd, Schneider, Semboloni, Shapiro, Spergel, T. D. Kitching, Takada, Takada, Taylor, Tegmark, Zentner   +57 more
core   +1 more source

A realistic assessment of the CTA sensitivity to dark matter annihilation [PDF]

, 2015
We estimate the sensitivity of the upcoming CTA gamma-ray telescope to DM annihilation at the Galactic centre, improving on previous analyses in a number of significant ways.
Bertone, Gianfranco, Scott, Pat, Silverwood, Hamish, Weniger, Christoph   +3 more
core   +3 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Conference summary: Workshop on Precision Astronomy with Fully Depleted CCDs (2014)

, 2015
Thick fully depleted CCDs, while enabling wide spectral response, also present challenges in understanding the systematic errors due to 3D charge transport. This 2014 Workshop on Precision Astronomy with Fully Depleted CCDs covered progress that has been
Tyson, J. A.
core   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Quantization (Systematic) [PDF]

, 2009
Contains fulltext : 75968.pdf (Publisher’s version ) (Open Access)
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source