Results 11 to 20 of about 5,145,453 (383)
Scientific Reports, 2021 Our previous study demonstrated increased expression of Heat shock protein (Hsp) 90 in the skin of patients with systemic sclerosis (SSc). We aimed to evaluate plasma Hsp90 in SSc and characterize its association with SSc-related features. Ninety-two SSc
H. Štorkánová +11 more
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Nature Reviews. Cancer, 2021 Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole.
Kamir J. Hiam-Galvez +2 more
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Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
Nature reviews. Immunology, 2021 Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically associated with other chronic inflammation-driven disorders, including cardio-metabolic, neurodegenerative and autoimmune diseases and cancer.
G. Hajishengallis, T. Chavakis
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Health Affairs, 2022 Racism is not always conscious, explicit, or readily visible-often it is systemic and structural. Systemic and structural racism are forms of racism that are pervasively and deeply embedded in systems, laws, written or unwritten policies, and entrenched ...
P. Braveman +4 more
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Molecular pathogenesis and systemic therapies for hepatocellular carcinoma
Nature Cancer, 2022 Hepatocellular carcinoma (HCC) remains one of the most prevalent and deadliest cancers. The poor outcome associated with HCC is dramatically changing due to the advent of effective systemic therapies.
J. Llovet +7 more
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Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases
Nature reviews. Immunology, 2022 Systemic autoimmune diseases are characterized by the failure of the immune system to differentiate self from non-self. These conditions are associated with significant morbidity and mortality, and they can affect many organs and systems, having ...
G. Wigerblad, M. Kaplan
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System-of-Systems Complexity [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 In Proceedings AiSoS 2013, arXiv:1311 ...
openaire +5 more sources
The blood–brain barrier in systemic infection and inflammation
Cellular & Molecular Immunology, 2021 The vascular blood–brain barrier is a highly regulated interface between the blood and brain. Its primary function is to protect central neurons while signaling the presence of systemic inflammation and infection to the brain to enable a protective ...
I. Galea
semanticscholar +1 more source
On the Flexibility of Systems in System of Systems Architecting
Procedia Computer Science, 2014 AbstractSystem of Systems (SoS) architecting requires analyzing a set of individual but interconnected systems simultaneously in order to build a communicating SoS, which can provide the capabilities needed. In general, the systems can provide a set of capabilities and the SoS architect needs to decide which systems to include in the SoS so that each ...
Hadi Farhangi +2 more
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Arthritis & Rheumatism, 2012 OBJECTIVE The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet ...
M. Petri +51 more
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