Results 31 to 40 of about 129,491 (262)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Literature review of impact assessment methodologies in the bioeconomy

open access: yesCleaner Environmental Systems
This study conducts a comprehensive review and analysis of the scientific literature focused on methodologies used to assess the impact of the bioeconomy.
Maria Ana Romero, José M. Gil
doaj   +1 more source

Science, innovation and society

open access: yesEFSA Journal, 2016
This session focused on emerging areas in biomedical research that are of key relevance to toxicology and, therefore, may influence EFSA's work. The impact on the way risk assessment is conducted in the area of food may be through the identification of ...
Frank Boelaert   +7 more
doaj   +1 more source

The Paradigms of Industry 4.0 and Circular Economy as Enabling Drivers for the Competitiveness of Businesses and Territories: The Case of an Italian Ceramic Tiles Manufacturing Company

open access: yesSocial Sciences, 2018
Sustainable development and the circular economy are two important issues for the future and the competitiveness of businesses. The programs for the integration of sustainability into industrial activities include the reconfiguration of production ...
Fernando E. Garcia-Muiña   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards a systemic assessment of environmental impact (SAEI) regarding alternative hydrosedimentological management practice in the Canal del Dique, Colombia

open access: yesIngeniería e Investigación, 2013
The Canal del Dique, located on the Colombian Caribbean Coast, can be seen as an "artificial" branch of the River Magdalena. Since its inception in 1650, it has undergone a series of interventions aimed at optimising river navigation between Cartagena ...
Leonel Vega Mora   +2 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Life Cycle Assessment of Swimming Goggles: Evaluating Environmental Impact and Consumer Awareness

open access: yesJournal of Experimental and Theoretical Analyses
This study evaluates the environmental impact of swimming goggles through a Life Cycle Assessment (LCA), comparing virgin and recycled polycarbonate models.
Vasilissa Nikonova   +6 more
doaj   +1 more source

Incorporating nexus ecolabels into household level food waste mitigation strategies: Environmental perspectives from life cycle assessment [PDF]

open access: yesJournal on Processing and Energy in Agriculture
This study provides a comprehensive evaluation of the economic and environmental impacts of food waste reduction through the implementation of Smart NEXUS Ecolabels. Employing the JRC Food Waste Prevention Calculator, the analysis centers on a optimistic-
Kitanovski Vladimir   +5 more
doaj   +1 more source

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