Results 111 to 120 of about 2,290,242 (288)

Associations of Raynaud's Phenomenon in Juvenile Onset Systemic Lupus Erythematosus

open access: yesVan Tıp Dergisi
INTRODUCTION: Raynaud's phenomenon (RP) is associated with mild disease in adults with systemic lupus erythematosus (SLE). Although RP is more frequently reported in juvenile onset SLE (jSLE) clinical associations were not studied.
Özge Baba   +2 more
doaj   +1 more source

Ocular Biometry Profile and Its Associations with Systemic and Demographic Factors in Thai Cataract Patients [PDF]

open access: yes
Anyarak Amornpetchsathaporn,1 Somporn Chantra,1 Kornkamol Annopawong,1 Kasem Seresirikachorn,1 Kittipong Kongsomboon,2 Boonsong Wanichwecharungruang1,3 1Department of Ophthalmology, Rajavithi Hospital and College of Medicine, Rangsit University, Bangkok,
Annopawong K   +5 more
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Systemic Inflammation Mediates the Associations Between Abdominal Obesity Indices and Lung Function Decline in a Chinese General Population

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Heng He, 1, 2 Bin Wang, 1, 2 Min Zhou, 1, 2 Limin Cao, 1, 2 Weihong Qiu, 1, 2 Ge Mu, 1, 2 Ailian Chen, 1, 2 Shijie Yang, 1, 2 Weihong Chen 1, 2 1Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College ...
He H   +8 more
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Associations between systemic inflammation indicators and nonalcoholic fatty liver disease: evidence from a prospective study

open access: yesFrontiers in Immunology
BackgroundAlthough inflammation has been linked to nonalcoholic fatty liver disease (NAFLD), most studies have focused only on a single indicator, leading to inconsistent results.
Hao Gong   +8 more
doaj   +1 more source

Prevalence and systemic associations of retinal vascular occlusions in Sub-Saharan Africa.

open access: yesAnn Afr Med, 2023
Okonkwo ON   +8 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

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