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Systemic Lymphoproliferative Diseases

Oral and Maxillofacial Surgery Clinics of North America, 2008
With advancements in diagnosis and treatment for lymphoma, it is important that physicians be up to date in the management of these lymphoproliferative disorders, their associated complications, and the complications of treatment. The importance of a thorough examination of the oro-facial complex and neck on all patients cannot be overemphasized.
Aaron, Liddell, Sidney L, Bourgeois
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Neuropathies in Systemic Disease

Seminars in Neurology, 2015
Most peripheral neuropathies result from systemic disease. In this review, the authors highlight the main clinical features, electrographic abnormalities, histopathological aspects and treatment, as well as the current, but still incomplete understanding of the pathophysiological mechanisms involved.
Michael P, Bowley, Allan H, Ropper
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Vitiligo as a systemic disease

Clinics in Dermatology, 2014
Vitiligo is an acquired depigmentary skin disorder of unknown etiology. Vitiligo is not only a disease of melanocytes of the skin. Human melanocytes are derived from the neural crest and are located on various parts of the body. The involvement of skin melanocytes is the most visible one, but a systemic involvement of melanocytes can be observed.
Torello, Lotti   +1 more
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The Heel in Systemic Disease

Clinics in Podiatric Medicine and Surgery, 1990
Heel pain is most commonly the result of mechanical abnormality in foot structure or function. Systemic disease, however, may also affect the heel, resulting in pain, deformity, or both of the rearfoot. This article discusses and reviews notable systemic conditions, exclusive of the seronegative spondyloarthropathies, which may produce subjective or ...
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The cornea and systemic diseases

Current Opinion in Ophthalmology, 1996
Multiple systemic diseases imply corneal involvement. Corneal pathology may also be a presenting sign or may herald a forthcoming relapse of chronic disease. The presence of ulcerative keratitis in patients with rheumatoid arthritis can be associated with systemic lethal vasculitis.
K A, Freissler, G E, Lang
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The Hand in Systemic Disease

The Journal of Bone & Joint Surgery, 1962
Common, and some uncommon, findings in the hand have been described and illustrated. The diagnostic importance of these findings has been emphasized in an attempt to extol the hand as a source of valuable information concerning the patient and his disease: "To one who examines it carefully the hand tells much concerning its owner; for in it is written
H B, BRADBURN, R A, CHASE, J M, FESSEL
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The cornea and systemic diseases

Current Opinion in Ophthalmology, 1995
Corneal involvement in systemic diseases is multifold. Dry eye syndrome may be associated with autoimmune diseases. Type I diabetes mellitus shows a positive correlation between HbA1c-level and dry eye syndrome. Autoimmune diseases and occasionally malignancies may be associated with ulcerative keratitis.
A M, Palmowski, K W, Ruprecht
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Psoriasis as a systemic disease

Clinics in Dermatology, 2014
Psoriasis is an inflammatory immune-mediated disease that affects the skin and has pathogenic effects with systemic impact. The relationship between psoriasis and comorbidities remains controversial. The hypothesis of a causative role of psoriasis in its cardiovascular and metabolic comorbidities is based on pathophysiologic concepts establishing a ...
Ivan, Grozdev   +2 more
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Respiratory System Disease

Pediatric Clinics of North America, 2016
Respiratory system involvement in cystic fibrosis is the leading cause of morbidity and mortality. Defects in the cystic fibrosis transmembrane regulator (CFTR) gene throughout the sinopulmonary tract result in recurrent infections with a variety of organisms including Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, and ...
Danielle M, Goetz, Shipra, Singh
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Osteoarthritis as a systemic disease

Nature Reviews Rheumatology
Osteoarthritis (OA) is a painful disorder of the synovial joints characterized by dysfunctional cellular metabolism and extracellular matrix degradation that activates maladaptive repair responses, including pro-inflammatory pathways of innate immunity.
Kelsey H. Collins   +3 more
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