Lung-Based, Exosome Inhibition Mediates Systemic Impacts Following Particulate Matter Exposure [PDF]
Particulate matter (PM) exposure is a global health issue that impacts both urban and rural communities. Residential communities in the Southwestern United States have expressed concerns regarding the health impacts of fugitive PM from rural, legacy mine-
Keegan Lopez +5 more
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Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice [PDF]
Background A very pure multi-walled carbon nanotube (MWCNT) that was shown to have very low toxicity in vitro, was evaluated for lung and systemic effects and distribution following inhalation exposure. Methods B6C3F1/N mice were exposed to varying doses
Christopher T. Migliaccio +7 more
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Systemic impacts of disruptions at maritime chokepoints [PDF]
Global trade relies on a small number of strategic passageways, so-called maritime chokepoints, which are vulnerable to disruptions. Yet, the exposure of countries to these disruptions has not been comprehensively assessed, inhibiting adequate ...
Jasper Verschuur +2 more
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Using project-based learning to teach project-based learning: lessons learned ,
This article reports the lessons learned using a project-based learning (PBL) approach for teaching the project-based learning methodology itself. This study was conducted with 33 graduate students from the Faculty of Education of the University of São ...
João Alberto Arantes do Amaral
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Systemic risk and compound vulnerability impact pathways of food insecurity in Somalia
In a strongly interconnected world, extreme and compound events pose systemic risks to food security and populations already vulnerable to the impacts of climate change.
Lisa Thalheimer +2 more
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Modelling systemic COVID-19 impacts in cities
The COVID-19 pandemic has impacted public health, the economy and society—both directly and indirectly. Few approaches exist to understand these complex impacts in a way that (1) acknowledges cross-sectoral interdependencies; (2) models how short-term ...
Lindsay Beevers +5 more
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Altered dietary behaviour during pregnancy impacts systemic metabolic phenotypes
RationaleEvidence suggests consumption of a Mediterranean diet (MD) can positively impact both maternal and offspring health, potentially mediated by a beneficial effect on inflammatory pathways.
Charlotte E. Rowley +20 more
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How do population movements fit within the framework of systemic risk?
Population movements are key elements shaping today's complex and interconnected societies. Movement of people underpins the circulation of capital, knowledge, ideas, culture, values and resources with systemic benefits but it also produces diverse risk ...
Serena Tagliacozzo +2 more
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A prototype Earth system impact metric that accounts for cross-scale interactions
Human activities are disrupting the Earth system’s biophysical processes, which underlie human wellbeing. The planetary boundary framework sets ‘safe’ global limits on these pressures, but a sub-global assessment of these pressures, their interactions ...
Steven J Lade +3 more
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Lessons from COVID-19 for managing transboundary climate risks and building resilience
COVID-19 has revealed how challenging it is to manage global, systemic and compounding crises. Like COVID-19, climate change impacts, and maladaptive responses to them, have potential to disrupt societies at multiple scales via networks of trade, finance,
Andrew K. Ringsmuth +20 more
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