Results 41 to 50 of about 3,323 (218)

Toward a framework for systemic multi-hazard and multi-risk assessment and management

iScience, 2023
Summary: In our increasingly interconnected world, natural hazards and their impacts spread across geographical, administrative, and sectoral boundaries.
Stefan Hochrainer-Stigler, Robert Trogrlić Šakić, Karina Reiter, Philip J. Ward, Marleen C. de Ruiter, Melanie J. Duncan, Silvia Torresan, Roxana Ciurean, Jaroslav Mysiak, Dana Stuparu, Stefania Gottardo   +10 more
doaj   +1 more source

The Impact of Systemic Inflammation on Neurodevelopment [PDF]

Trends in Molecular Medicine, 2018
Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children's neurodevelopment.
Nona M, Jiang, Maureen, Cowan, Shannon N, Moonah, William A, Petri   +3 more
openaire   +2 more sources

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Systemic impacts of disruptions at maritime chokepoints

Nature Communications
Global trade relies on a small number of strategic passageways, so-called maritime chokepoints, which are vulnerable to disruptions. Yet, the exposure of countries to these disruptions has not been comprehensively assessed, inhibiting adequate ...
Jasper Verschuur, Johannes Lumma, Jim W. Hall   +2 more
doaj   +1 more source

Peri-implantitis and systemic inflammation: A critical update

Saudi Dental Journal, 2023
Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy.
Nasser M. Assery, Carlos A. Jurado, Mansour K. Assery, Kelvin I. Afrashtehfar   +3 more
doaj   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

Managing the Systemic Impact of Periodontitis

Medicina, 2022
Periodontitis is a microbially driven host-mediated disease that leads to loss of periodontal attachment and bone. It is associated with elevation of systemic inflammatory markers and with the presence of systemic co-morbidities. Furthermore, periodontal treatment leads to a 24–48 h-long acute local and systemic inflammatory response.
Giuseppe Mainas, Mark Ide, Manfredi Rizzo, Antonio Magan-Fernandez, Francisco Mesa, Luigi Nibali   +5 more
openaire   +5 more sources

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Ferroptosis in periodontitis: mechanisms, impacts, and systemic connections

Cell Death Discovery
Periodontitis is a chronic inflammatory disease initiated by plaque microorganisms, with the regulatory mechanisms of its progression being a primary research focus.
Peng Guan, Qijun Ruan, Jiatong Li, Mengying Xi, Weijuan Qi, Kang I. Ko, Jia Ni   +6 more
doaj   +1 more source

The Impact of Autocorrelation on Queuing Systems [PDF]

Management Science, 1993
The performance of single-server queues with independent interarrival intervals and service demands is well understood, and often analytically tractable. In particular, the M/M/1 queue has been thoroughly studied, due to its analytical tractability. Little is known, though, when autocorrelation is introduced into interarrival times or service demands,
Miron Livny, Benjamin Melamed, Athanassios K. Tsiolis   +2 more
openaire   +2 more sources