Results 61 to 70 of about 3,045,517 (253)
Women of Color for Systemic Change. Harmony Wright interview
, 2017 Interview with Harmony Wright of Women of Color for Systemic ...
Coronel, Micaela, Wright, Harmony
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
PLoS ONE, 2016 Nutritional immunity is a process whereby an infected host manipulates essential micronutrients to defend against an invading pathogen. We reveal a dynamic aspect of nutritional immunity during infection that involves copper assimilation.
Joanna Mackie +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in Public HealthBackgroundPractitioners have reported negative emotional impacts following client suicide. However, there is a paucity of literature exploring the impacts of working with clients engaging in suicidal behavior and on the impacts of repeat exposure to ...
Megan Collisson, Jacinta Hawgood
doaj +1 more source
Hydrologic impacts meeting report
, 2014 On Monday, March 3rd, 2014, the Pacific Climate Impacts Consortium (PCIC) held the final of three meetings focused on the themes of the consortium. These meetings are intended to both introduce some of the latest work of the themes, but also to gather ...
Pacific Climate Impacts Consortium (PCIC)
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Exploring the impacts of colostrum on systemic immune development in dairy calves
Journal of Dairy Science: Colostrum provides essential immune components, but its role in shaping neonatal immune development is not fully understood. Twenty-four Holstein calves were randomly assigned to 1 of 3 treatments: fresh colostrum (n = 8), frozen colostrum (n = 8), or ...
M. Cid de la Paz +5 more
doaj +1 more source
Ending the Document Game, Connecting and Transforming Your Healthcare Through Information Technology
, 2005 Report of the Commission on Systemic Interoperability proposes an information-connected healthcare system which would allow healthcare providers rapid access to individuals' medical information while still protecting consumers' privacy and supporting ...
Commission on Systemic Interoperability
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source